2016 PUBLICATIONS

Dahl JU, Koldewey P, Bardwell JC, Jakob U. (2016) Detection of the pH-dependent Activity of Escherichia coli Chaperone HdeB In Vitro and In Vivo.  J Vis Exp. 2016 Oct 23;(116). doi: 10.3791/54527. PubMed

Scott Horowitz & James C.A. Bardwell (2016) RNAs as chaperones RNA Biology, 13:12, 1228-1231, DOI: 10.1080/15476286.2016.1247147 PubMed

Johansson KE, Johansen NT, Christensen S, Horowitz S, Bardwell JC, Olsen JG, Willemoës M, Lindorff-Larsen K, Ferkinghoff-Borg J, Hamelryck T, Winther JR. (2016) Computational redesign of thioredoxin is hypersensitive towards minor conformational changes in the backbone template. J Mol Biol. 2016 Sep 19. pii: S0022-2836(16)30378-3. doi: 10.1016/j.jmb.2016.09.013. PubMed

Horowitz S, Koepnick B, Martin R, Tymieniecki A, Winburn AA, Cooper S, Flatten J, Rogawski DS, Koropatkin NM, Hailu TT, Jain N, Koldewey P, Ahlstrom LS, Chapman MR, Sikkema AP, Skiba MA, Maloney FP, Beinlich FR; Foldit Players; University of Michigan students, Popović Z, Baker D, Khatib F, Bardwell JC. (2016). Determining crystal structures through crowdsourcing and coursework. Nat. Commun.2016 Sep 16;7:12549. doi: 10.1038/ncomms12549. PubMed
This paper was the subject of a Marketplace Tech interview.

Sciore A, Su M, Koldewey P, Eschweiler JD, Diffley KA, Linhares BM, Ruotolo BT, Bardwell JC, Skiniotis G, Marsh EN. (2016) Flexible, symmetry-directed approach to assembling protein cages. PNAS. 2016 Aug 2;113(31):8681-6. doi: 10.1073/pnas.1606013113. Epub 2016 Jul 18. PubMed

Loïc Salmon, Logan S. Ahlstrom, Scott Horowitz, Alex Dickson, Charles L. Brooks, and James C. A. Bardwell. (2016) Capturing a dynamic chaperone-substrate interaction using NMR-informed molecular modeling JACS. DOI:10.1021/jacs.6b02382 Epub July 14, 2016 PubMed

Koldewey P, Stull F, Horowitz S, Martin R, Bardwell JCA. (2016) Forces Driving Chaperone Action. Cell. 2016 Jun 9. pii: S0092-8674(16)30657-2. doi: 10.1016/j.cell.2016.05.054. PubMed  This paper was the subject of a News and Views [PDF]  citation in NSMB by Patricia L. Clark and Adrian H. Elcock. 

Horowitz S, Salmon L, Koldewey P, Ahlstrom L, Martin R, Quan S, Afonine PV, van den Bedem H, Wang L, Xu Q, Trievel RC, Brooks CL, Bardwell JCA. (2016) Visualizing Chaperone-assisted Folding. Nature Struct. Mol. Biol. 2016 Jul;23(7):691-7. doi: 10.1038/nsmb.3237. Epub 2016 May 30. PubMed  This paper was the subject of a News and Views citation in NSMB by Patricia L. Clark and Adrian H. Elcock. 

Docter BE, Horowitz S, Gray MJ, Jakob U, and Bardwell JCA (2016) Do Nucleic Acids Moonlight as Molecular Chaperones? Nucleic Acids Research. 2016 Jun 2;44(10):4835-45. doi: 10.1093/nar/gkw291. Epub 2016 Apr 21.  PubMed 

Groitl B, Horowitz S, Makepeace KA, Petrotchenko EV, Borchers CH, Reichmann D, Bardwell JC, Jakob U. (2016) Protein unfolding as a switch from self-recognition to high-affinity client binding.  Nat Commun. 2016 Jan 20;7:10357. doi: 10.1038/ncomms10357. PMID: 26787517 PubMed

Stull F, Koldewey P, Humes JR, Radford SE, Bardwell JC. (2016). Substrate protein folds while it is bound to the ATP-independent chaperone Spy.  Nat Struct Mol Biol. 2016 Jan;23(1):53-8. doi: 10.1038/nsmb.3133. Epub 2015 Nov 30. PMID: 26619265 PubMed   This paper was the subject of a News and Views  citation in NSMB by Patricia L. Clark and Adrian H. Elcock.