Chalk Talk Schedule

2016 Fall Term Chalk Talk Schedule

October 21-Stephanie Gates, “Using Cryo-EM to Decipher the Mechanism of Hsp104 Disaggregation

November 22-Dr. Alison Narayan, “Harnessing the Synthetic Utility of Biosynthetic Enzymes

2016 Winter Term Chalk Talk Schedule

January 25- Will Kaplan, Cardiotonic steroids and the synthesis of 19-hydroxysarmentogenin
February 22 – Evan Schramm, Allosteric modulation of opioid G protein-coupled receptors
March 21- Lyanne Gómez-Rodríguez, Isolation, Structural Elucidation and Biosynthetic Characterization of HIV-1 Nef Accessory Protein Inhibitors
April 18- Osvaldo Cruz

All Chalk Talks are in Chem 2404, 12:30 pm-2 pm

2015 Fall Term Chalk Talk Schedule

September 22- Sarah Haynes, Enhancing proteomics with ion mobility separation
October 19- Desiree Garcia-Torres, Regulation of small GTPase prenylation by SmgGDS proteins
November 17- Eric Lachacz
December 15- David Rogawski

All Chalk Talks are in Chem 2742, 12:00pm-1:30pm

2015 Winter Term Chalk Talk Schedule

January 21, Chem 1201– Eric Lachacz, An Irreversible Fluorescent Probe for c-Src Visualization
February 19, Chem 2404-  Will Kaplan, Cu-BOX Catalyzed Asymmetric Michael Additions and Synthetic Methodologies for Polyoxygenated Steroids
Dr. Jayakrishnan Nandakumar, Preventing aging versus promoting cancer — Telomerase, a double-edged sword
March 18, Chem 1201– Elizabeth Abshire, Characterization of human Nocturnin: a circadian deadenylase implicated in diet induced obesity
Dr. Amanda Garner, Targeting Translational Control in Cancer
April 23, Chem 2404– Carol Ann Pitcairn, Investigating the regulation of histone deacetylase 8
Dr. Patrick O’Brien, DNA damage and mechanisms of DNA repair

2014 Fall Term Chalk Talk Schedule

September 23, Chem 2404– David Rogawski, Intramolecular Regulation of Catalysis in the SET Domain of the ASH1L Histone Methyltransferase 
October 24, Chem 1201- Rachel Pricer
November 21, Chem 1201- Frank Kwarcinski, Hybrid Fragment Tethering for Designing Selective Kinase Inhibitors
December 19, Chem 1201- Osvaldo Cruz, Activation of Phospholipase C isozymes by Heterotrimeric G proteins

All Chalk Talks are 12:00pm-1:30pm


2014 WINTER Term Chalk Talk Schedule

January 22
February 19
March 19
April 23
May 21

All Chalk Talks are held in 1201 CHEM, 12:00pm-1:30pm



Sept 19, 2012 Using Irreversible Kinase Inhibitors to Study Protein Dynamics- by Frank Kwarcinski, Medicinal Chemistry, Soellner LabThe p300 CH1 and HAT domains regulate NANOG expression in cancer cells – by Conor Doss, Chemical Biology, Mapp Lab
April 18, 2012 Carol Ann Pitcairn 12:00pm-1:00pm-1201 CHEMISTRY BLDG
March 21, 2012 Alison Tebo & Steffen Bernard 12:00pm-1:00pm-1201 CHEMISTRY BLDG
February 22, 2012 Derek Lyons & Ronald Jenkins Mapping Mutations, Eliminating Errors, Finding Frameshifts -Derek LyonsHigh-throughput Screening to Identify Molecular Probes of Early Acyltransferases of Lipid A Biosynthesis– Ronald Jenkins
Jan 18, 2012 Solymar Negrettii & Conor Doss Exploring Macrolide P450 enzymes as bio-catalysts for C-H activation-Solymar NegrettiInvestigating the biological effects of CBP KIX domain inhibition by depside natural products- Conor Doss
Dec 14, 2011 Carol Ann Pitcairn & Melissa Zastrow Determining the metal selectivity of histone deacetylase 8 -Carol Ann PitcairnKinetic studies of de novo designed zinc peptides: incorporating second-sphere interactions- Melissa Zastrow
Nov 16, 2011 Frank Kwarcinski & Conor Doss Selective Protein Tyrosine Kinase Inhibition Through Non-Conserved Binding Modes -Frank KwarcinskiSmall molecule inhibition of NANOG in cancer-initiating cells- Conor Doss
Oct 19, 2011 Jon Whicher & Erin Miller Characterization of Curacin Docking Domains “-Jon WhicherThe interaction of AlkA and Lesion Containing DNA”- Erin Miller
Sept. 21, 2011 Solymar Negretti & Steffen Bernard Synthesis and evaluation of unnatural substrates for C-H activation studies employing macrolide biosynthethic P450s as catalysts -Solymar NegrettiUsing a peptide mimic of an acyl carrier protein domain in structural studies of polyketide synthase ketoreductase domains– Steffen Bernard
April 27,2011 Jon Whicher & Derek Lyons Characterization of the Docking Domains from the Curacin A biosynthetic Pathway  – Jon WhicherGlycosylase Recognition of Damaged DNA: Balancing Mutagenesis and Repair – Derek Lyons
March 30,2011 Steffen Bernard & Chris Rath The Structural Basis of Stereochemistry in Polyketide Natural Products  – Steffen BernardAlternative methodologies for exploring the predicted biochemistry of the ET-743 biosynthetic – Chris Rath
Feb. 23,2011 Solymar Negretti & Melissa Zastrow Evaluating PikC as a catalyst for C-H activation through substrate engineering – Solymar NegrettiDe novo designed metallopeptides to mimic metal sites in nature – Melissa Zastrow
Jan. 26, 2011 Chris Taylor & Jeff Hill Small molecule modulation of erbB2 overexpression -Chris TaylorCorronoid Iron Sulfur Protein: Key Component of the Wood-Ljungdahl Pathway – Jeff Hill
Jan. 19, 2011 Donald Raymond & Ronald Jenkins Meeting held with CBI-IDP students “Structural biology of Rift Valley fever virus nucleocapsid protein” – Donald Raymond”Probing Early Acyltransferases of Lipid A Biosynthesis”- Ronald Jenkins
Nov. 24, 2010 Melissa Zastrow & Chris Rath Hydrolytic catalysis and structural stabilization in a de novo-designed metalloprotein” – Melissa ZastrowCulture-independent characterization of a key gene cluster in a marine tunicate bacterial symbiont system: multi-omic investigations into ET-743 biosynthesis- Chris Rath
Oct. 27, 2010 Derek Lyons & Jonathon Whicher Rebelious Repair: Mutations Caused by DNA Repair – Derek LyonsInvestigating the stereochemical control of polyketide synthase ketoreductases – Jonathon Whicher
Sept. 29, 2010 Solymar Negretti & Ronald Jenkins Synthesis of Unnatural Substrates for PikC Oxidation Studies – Soylmar NegrettiPhage Display for Discovery of Peptides Probing Early Acyltransferases of Lipid A Biosynthesi” – Ron Jenkins
April 14, 2010 Matt Leathen The facile preparation of protected benzylic and heteroarylmethyl amines via room temperature Curtius rearrangements
Christopher Taylor Curbing overexpression of erbB2 by mimicking a transcriptional activation domain
Mar 24, 2010 Donald Raymond Structural Biology of RNA Viral Protein
Dustin Patterson Symmetry Assembled Protein Cages
Feb. 17, 2010 Jonathon Whicher 2.17Å structure of a thioesterase from the prodiginine biosythetic pathway with a novel role in intermediate transfer
April 29, 2008 Matt Leathen & Curtis Schneider
Meeting held with CBI-IDP students this month
Mar 25, 2008 Discussion on choosing a post-doc and career development
led by Professor Pecoraro
Feb 26, 2008 Levi Blazer & Edgar Lee
Jan 29, 2008 Sara Buhrlage “Regulation of Transcription with Small Molecules”
Susan Wiedner “Synthetic Studies Toward Aziridinomitosenes”
Meeting held with CBI-IDP students this month
Nov 27, 2007 Chris Rath “Utilizing mass spectrometry to investigate polyketide
Bob Rarig “Hydroboration of homoallylic alcohols”
Oct 30, 2007 Becky Roof “Peptide Ligands of Regulators of G-Protein Signaling
4 (RGS4) from a One-Bead, One-Compound Library Screen”.
Dustin Patterson “Investigations in Coiled-coil Assembly of Protein
Sep 25, 2007 Prof. Pecoraro Introduction