Publications

Selected Publications (from > 220 peer-reviewed publications)

Parikh, V., Kozak, R., Martinez, V., & Sarter, M. (2007). Prefrontal acetylcholine controls cue detection on multiple time scales. Neuron, 56, 141-154. PubMed

Parikh, V., Man, K., Decker, M.W., & Sarter, M. (2008). Glutamatergic contributions to nAChR agonist-evoked cholinergic transients in the prefrontal cortex. Journal of Neuroscience, 28, 3769-3780. PubMed

Sarter, M., Parikh, V., & Howe, W.M. (2009). Phasic acetylcholine release and the volume transmission hypothesis: time to move on. Nature Reviews Neuroscience, 10, 383-390. PubMed

Parikh, V., Ji, J., Decker, M.W., & Sarter, M. (2010). Prefrontal β2 subunit-containing and α7 nAChRs differentially control glutamatergic and cholinergic signaling. Journal of Neuroscience, 30, 3518-3530. PubMed

Hasselmo, M.E., & Sarter, M. (2011). Modes and models of forebrain cholinergic neuromodulation of cognition. Neuropsychopharmacology Reviews, 36, 52-73. PubMed

Sarter, M., & Tricklebank, M. (2012). Revitalizing psychiatric drug discovery. Nature Reviews Drug Discovery, 11, 423-424. PubMed

Paolone, G., Lee, T.M., & Sarter, M. (2012). Time to pay attention: attentional performance time-stamped prefrontal cholinergic activation, diurnality and performance. Journal of Neuroscience, 32, 12115-12128. PubMed

Parikh, V., Howe, W.M., Welchko, R.C., Naughton, S.X., D’Amore, D.E., Han, D.H., Deo, M., Turner, D.L., & Sarter, M. (2013). Diminished trkA receptor signaling reveals cholinergic-attentional vulnerability to aging. European Journal of Neuroscience, 37, 278-293. PubMed

Parikh, V., St. Peters, M., Blakely, R.D., & Sarter, M. (2013). The presynaptic choline transporter imposes limits on sustained cortical acetylcholine release and attention. Journal of Neuroscience, 33, 2326-2337. PubMed

Demeter, E., Guthrie, S.K., Taylor, S.T., Sarter, M., & Lustig C. (2013). Increased distractor vulnerability but preserved vigilance in patients with schizophrenia: evidence from a translational sustained attention task. Schizophrenia Research, 144, 136-141. PubMed

Paolone, G., Angelakos, C.C., Meyer, P., Robinson, T.E., & Sarter, M. (2013). Cholinergic control over attention in rats prone to attribute incentive salience to reward cues. Journal of Neuroscience, 33, 8321-8335. PubMed

Howe, M.W., Berry, A.S., Francois, F., Gilmour, G., Carp, J.M., Tricklebank, M., Lustig, C., & Sarter, M. (2013). Prefrontal cholinergic mechanisms instigating shifts from monitoring for cues to cue-guided performance: Converging electrochemical and fMRI evidence from rats and humans. Journal of Neuroscience, 33, 8742-8752. PubMed

Paolone, G., Mallory, C.S., & Blakely, R.D., & Sarter, M. (2013). Monitoring cholinergic neurotransmission during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits. Neuropharmacology, 75, 274-285. PubMed

Kucinski, A., Paolone, G., Bradshaw, M., Albin, R.L., & Sarter, M. (2013). Modeling fall propensity in Parkinson’s disease: Deficits in the attentional control of complex movements in rats with cortical-cholinergic and striatal-dopaminergic deafferentation. Journal of Neuroscience, 33, 16522-16539. PubMed

Koshy Cherian, A., Gritton, H., Johnson, D.E., Young, D., Kozak, R., & Sarter, M, (2014). A systemically-available kynurenine aminotransferase II (KAT II) inhibitor restores nicotine-evoked glutamatergic activity in the cortex of rats. Neuropharmacology, 82: 41-48. PubMed

Holmstrand, E.C., Lund, D., Cherian, A.K., Wright, J., Martin, R.F., Ennis, E.A., Stanwood, G.D., Sarter, M., & Blakely, R.D. (2014). Transgenic overexpression of the presynaptic choline transporter elevates acetylcholine levels and augments motor endurance. Neurochemistry International, 73, 217-228. PubMed

Sarter, M., Lustig, C., Howe, W.M., Gritton, H., & Berry, A.S. (2014). Deterministic functions of cortical acetylcholine. European Journal of Neuroscience, 39, 1912-1920. PubMed

Sarter, M., Albin, R.L., Kucinski, A., & Lustig, C. (2014). Where attention falls: increased risk of falls from the converging impact of cortical cholinergic and midbrain dopamine loss on striatal function. Experimental Neurology, 257, 120-129. PubMed

Berry, A.S., Demeter, E., Sabhapathy, S., English, B., Blakely, R.D., Sarter, M., & Lustig, C. (2014). Disposed to distraction? Genetic variation in the cholinergic system influences distractibility but not time-on-task effects. Journal of Cognitive Neuroscience, 25, 1981-1991. PubMed

Sarter, M. (2015). Behavioral-cognitive targets for cholinergic enhancement. Current Opinion in Behavioral Sciences, 4, 22-26. ScienceDirect

Kucinski, A., Albin, R.L., Lustig, C., & Sarter, M. (2015). Modeling fall propensity in Parkinson’s disease: extensive striatal dopamine loss-associated freezing of gait. Behavioural Brain Research, 282, 155-164. PubMed

Berry, A.S., Blakely, R.D., Sarter, M., & Lustig, C. (2015). Cholinergic capacity mediates prefrontal engagement during challenges to attention: evidence from imaging genetics. NeuroImage, 108, 386-395. PubMed

Sarter, M., & Kim, Y. (2015). Interpreting chemical neurotransmission in vivo: techniques, time scales and theories. ACS Chemical Neuroscience, 6, 8-10. PubMed

Gritton, H.J., Howe, M.W., Mallory, C.S., Hetrick, V.L., Berke, J.D., & Sarter, M. (2016). Cortical cholinergic signaling controls the detection of cues. Proceedings of the National Academy of Sciences, 113, E1089-1097. PubMed

Sarter, M., Lustig, C., Berry, A.S., Gritton, H., Howe, W.M., & Parikh, V. (2016). What do phasic cholinergic signals do? Neurobiology of Learning and Memory, 130, 145-151. PubMed

Sarter, M., Lustig, C., Blakely, R.D., & Koshy Cherian, A. (2016). Cholinergic genetics of visual attention: human and mouse choline transporter capacity variants influence distractibility. Special Issue: Influence of the cholinergic system on visual processing. Journal of Physiology (Paris), in press. ScienceDirect

Lustig, C., & Sarter, M. (2016). Attention and the cholinergic system: relevance to schizophrenia. Current Topics in Behavioral Neuroscience (Special Issue: Translational Neuropsychopharmacology, edited by T. W. Robbins and B.J. Shahakian). PubMed

Kucinski, A., de Jong, I.E.M., & Sarter, M. (2016). Reducing falls in Parkinson’s disease: Interactions between donepezil and the 5-HT6 receptor antagonist idalopirdine on falls in a rat model of impaired cognitive control of complex movements. European Journal of Neuroscience. PubMed

Pitchers, K.K., Wood, T.R., Skrzynski, C.J., Robinson, T.E., & Sarter, M. (2016). The ability of cocaine and cocaine-associated cues to compete for attention. Behavioural Brain Research. PubMed

Kim, K., Müller, M.L.T., Bohnen, N.I., Sarter, M., & Lustig, C. (2017). Thalamic cholinergic innervation makes a specific bottom-up contribution to signal detection: Evidence from Parkinson’s Disease patients with defined cholinergic losses. NeuroImage, in press. PubMed

Berry, A.S., Sarter, M., & Lustig, C. (2017). Distinct frontoparietal networks underlying attentional effort and cognitive control. Journal of Cognitive Neuroscience, in press.

Koshy Cherian, A., Kucinski, A., Pitchers, K., Yegla, B., Parikh, V., Kim, Y., Valuskova, P., Gurnani, S., Lindsley, C.W., Blakely, R.D., & Sarter, M. (2017). Unresponsive choline transporter as a trait neuromarker and a causal mediator of bottom-up attentional biases. Journal of Neuroscience, in press. PubMed

Howe, W.M., Gritton, H.J., Lusk, N., Roberts, E.A., Hetrick, V., Berke, J.D., & Sarter, M. (2017). Phasic acetylcholine release in prefrontal cortex promotes gamma oscillations and theta-gamma coupling during cue detection. Journal of Neuroscience, in press. PubMed