Audrey defends her dissertation!
Congratulation to Dr. Audrey Tolbert on successfully defending her dissertation today.
“Visible, Near-Infrared, and Dual-Range Luminescence Spanning the 4f Series Sensitized bu a Gallium(III)/Lanthanide(III) Metallacrown Structure”
Our latest Metallacrown paper on a new series of dimeric Ga(III)/Ln(III) metallacrowns bridged with four hydroxyl groups and capable of sensitizing all luminescent lanthanide ions.
Our latest two Peptide papers demonstrating the great utility of metallopeptides:
- Making of Breaking Metal-Dependent Catalytic Activity: The Role of Stammers in Designed Three-Stranded Coiled Coils”
- “The pH-Induced Selectivity Between Cysteine or Histidine Coordinated Heme in an Artificial α-Helical Metalloprotein”
“Dy3+ White Light Emission Can Be Finely Controlled by Tuning the First Coordination Sphere of Ga3+/Dy3+ Metallacrown Complexes”
Our latest Metallacrown paper on the analysis of a series of five Ga3+/Dy3+ MCs for their White Light Emission (WLE) properties. Read in JACS!
Our latest Metallopeptide paper on our efforts to rationally design copper proteins with a CuHis2CysGlu binding sites with either green or blue copper chromophores using mutation strategies that have proven successful in native cupredoxins.
Read in JACS!
“[Ga3+8Sm3+2, Ga3+8Tb3+2] Metallacrowns are Highly Promising Ratiometric Luminescent Molecular Nanothermometers Operating at Physiologically Relevant Temperatures”
Our latest Metallopeptide paper is a review on protein design efforts to create de novo metalloproteins within alpha‐helical scaffolds. Read in Angewandte Chemie International Ed!
Peculiarities of crystal structures and photophysical properties of GaIII/LnIII metallacrowns with a non-planar [12-MC-4] core
Our latest Metallacrown paper on X-ray single crystal analysis revealing two types of structures depending on whether the nitrate counterion in the metallacrown coordinates or not to the Ln(III) center. Read it in Inorganic Chemistry Frontiers!
Our latest Metallopeptide paper showing how it is possible to form pure heterotrimeric three-stranded coiled coils by combining three distinct characteristics: (1) a cysteine sulfur layer for metal coordination, (2) a thiophilic, trigonal pyramidal metalloid (Pb(ii)) that binds to these sulfurs and (3) an adjacent layer of reduced steric bulk generating a cavity where water can hydrogen bond to the cysteine sulfur atoms. Read it in Nature Chemistry!
Our latest paper on Superoxide dismutases (SODs) shows that rationally designed proteins with well-defined three-dimensional structures offer new opportunities for obtaining functional SOD mimics. Find it in Chemistry A European Journal!
Prof. Pecoraro elected as President of SBIC 2020-2022
Congratulations to Prof. Pecoraro on becoming the newest President of the Society of Biological Inorganic Chemistry (SBIC)! He will hold the position from October 2020 to September 2022.
The results are in! @SBICofficial has successfully completed the election cycle for 2019.
— SBIC (@SBICofficial) October 12, 2019
Here is our latest paper on Metallacrown functionalization for the development of biomodal imaging agents. We show that our luminescent 12-MC-4 dimer structures can be synthetically modified to have 4, 8, or 12 iodines, resulting on a complex capable of X-ray attenuation and luminescence. Find it in Chemistry A European Journal!