Our research focuses on the development of methods and applications of ion mobility mass spectrometry (IM-MS) to elucidate structures of proteins and protein complexes. Some of our primary research areas include:
- IM-MS to study different proteins/protein complexes
- Collision induced unfolding fundamental and applications
- Developing software for data analysis
- Developing algorithms to model protein assemblies
- Developing methods to study:
- Structural ensembles
- Membrane proteins
- Intrinsically disordered proteins
- Biotherapeutic proteins
- Instrumentation and methodology development:
- Ion Sources
- Charge Manipulation
- High-throughput screening
- And more
Please visit all the research projects in the website for more details.
There are no special pre-requisites to join the lab other than enthusiasm for learning about native mass spectrometry and good work ethic.
Please click here for details on applying to participate in undergraduate research.
Please click here for details on applying to graduate school.
Please email Prof. Brandon Ruotolo for availability and additional information.