Publications on Pubmed            Google Scholar            Research Gate


Tarnopol RL, Bowden S, Hinkle K, Balakrishnan K, Nishii A, Kaczmarek CJ, Pawloski T, Vecchiarelli AG*. Lessons from a Minimal Genome: What Are the Essential Organizing Principles of a Cell Built from Scratch? Chembiochem

  • All authors are undergraduates from the MCDB 401 class of 2019 “Building the Synthetic Cell”


MacCready JS, Hakim P, Young EJ, Hu L, Liu J, Osteryoung KW, Vecchiarelli AG*, Ducat DC*. Protein gradients on the nucleoid position the carbon-fixing organelles of cyanobacteria. eLife

* Co-corresponding authors

MacCready JS & Vecchiarelli AG*. In long bacterial cells, the Min system can act off-center. Mol Micro

Mizuuchi K & Vecchiarelli AG*Mechanistic insights of the Min oscillator via cell-free reconstitution and imaging. Phys Biol


Hu L, Vecchiarelli AG, Mizuuchi K, Neuman KC & Liu J. Brownian ratchet mechanisms of ParA-mediated partitioning. Plasmid

Hu L, Vecchiarelli AG, Mizuuchi K, Neuman KC & Liu J. Brownian Ratchet Mechanism for Faithful Segregation of Low-Copy-Number Plasmids. Biophys J

Pre-University of Michigan


Vecchiarelli AG, Li M, Mizuuchi M, Hwang LC, Seol Y, Neuman KC & Mizuuchi K.Membrane-bound MinDE complex acts as a toggle switch that drives Min oscillation coupled to cytoplasmic depletion of MinDPNAS


Longhua Hu, Vecchiarelli AG, Mizuuchi K, Neuman KC & Liu J. Directed and persistent movement arises from mechanochemistry of the ParA/ParB system. PNAS, E7055

Vecchiarelli AG*, Taylor JA & Mizuuchi K. ParAB motility reconstitution. Building a Cell from its Component Parts. Methods in Cell Biology 128, Chapter 13

* Corresponding author

Vecchiarelli AG, Seol Y, Neuman KC & Mizuuchi K. A moving ParA gradient on the nucleoid directs subcellular cargo transport via a chemophoresis forceBioArchitecture 4, 154


Vecchiarelli AG, Li M, Mizuuchi M & Mizuuchi K. Differential affinities of MinD and MinE to anionic phospholipid influence Min patterning dynamics in vitro. Mol Microbiol 93, 453

Vecchiarelli AG, Neuman KC & Mizuuchi K. A propagating ATPase gradient drive transport of surface-confined cellular cargoPNAS 111, 4880


Vecchiarelli AG, Havey JC, Ing L, Wong E, Waples W & Funnell BE. Dissection of the ATPase active site of P1 ParA reveals multiple active forms essential for plasmid partition. J Biol Chem 288, 17823

Vecchiarelli AG, Hwang LC & Mizuuchi K. Cell-free study of F plasmid partition provides evidence for cargo transport by a diffusion-ratchet mechanism. PNAS 110, E1390

Hwang LC*, Vecchiarelli AG*, Han YW, Mizuuchi M, Harada Y, Funnell BE & Mizuuchi K. ParA-mediated plasmid partition driven by protein pattern self-organization.EMBO J 32, 1238

* Equal Contribution

Vecchiarelli AG & Funnell BE. Probing the N-terminus of ParB using cysteine-scanning mutagenesis & thiol modification. Plasmid 70, 86


Vecchiarelli AG, Mizuuchi K & Funnell BE. Surfing biological surfaces: exploiting the nucleoid for partition and transport in bacteria. Mol Microbiol 86, 513

Havey JC, Vecchiarelli AG & Funnel BE. ATP-regulated interactions between P1 ParA, ParB & non-specific DNA that are stabilized by the plasmid partition site. Nucl Acids Res 40, 801


Vecchiarelli AG, Han YW, Tan X, Mizuuchi M, Ghirlando R, Biertümpfel C, Funnell BE & Mizuuchi K. ATP control of dynamic P1 ParA-DNA interactions: a key role for the nucleoid in plasmid partition. Mol Microbiol 78, 78


Vecchiarelli AG, Schumacher MA & Funnell BE. P1 partition complex assembly involves several modes of protein-DNA recognition. J Biol Chem 282, 10944