Selected Publications

Cadigan, K. M. (2012). “TCFs and Wnt/beta-catenin Signaling: More than one way to throw the Switch.” Curr. Topics in Dev. Biology 98: 1-34. PubMed

Archbold, H. A., Yang, Y. X. Chen, L. and Cadigan, K. M. (2012). “How can they do Wnt they do: regulation of transcription by Wnt/β-catenin signaling.” Acta Physiologica 204: 74-109.PubMed

Bhambhani, C., Chang, J. L., Akey, D. L. and Cadigan, K. M. (2011). “The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets.” EMBO J. 30: 2031-2043. PubMed

Cadigan, K. M. and M. Peifer (2009). “Wnt signaling from development to disease: Insights from model systems.” Cold Spring Harbor Perspectives on Biology 1: a002881

Kennell J. A. and Cadigan, K. M. (2009). “APC and β-catenin degradation.” Adv. Exp. Med. Biol. 656: 1-12.

Chang, M. V., Chang, J. L., Gangopadhyay, A., Shearer, A. and Cadigan, K. M. (2008). “Activation of Wingless targets requires bipartite recognition of DNA by TCF.” Curr. Biol. 18: 1877-1881. PubMed

Cadigan, K. M. (2008). “Wnt-βετα-catenin signaling.” Curr. Biol. 18: R943-947.

Liu, Y. I., Chang, M. V., Li, H. E., Barolo, S., Chang, J. L., Blauwkamp, T. A. and Cadigan, K.M. (2008). “The chromatin remodelers ISWI and ACF1 directly repress Wingless transcriptional targets.” Dev. Biol. 323: 41-52. PubMed

Kennell, J. Gerin, I., MacDougald, O. A. and Cadigan, K. M. (2008). “The microRNA miR-8 is a conserved negative regulator of Wnt signaling.” Proc. Natl. Acad. Sci. USA 105: 15417-15422. PubMed

Chang, J. L., Chang, M. V., Barolo, S. and Cadigan, K. M. (2008). “Regulation of the feedback antagonist naked cuticle by Wingless signaling.” Dev. Biol. 321: 446-454. PubMed

Blauwkamp, T. A., Chang, M. V. and Cadigan, K. M. (2008). “Novel TCF Binding Sites Specify Transcriptional Repression by Wnt Signaling.” EMBO J. 27: 436-446. PubMed

Cadigan, K. M. (2008). “Wnt/β-catenin signaling: turning the switch.” Dev. Cell 14: 322-323.PubMed

Parker, D. S., Ni, Y. Y., Chang, J. L., Li, J. and Cadigan, K. M. (2008). “Wingless signaling induces widespread chromatin remodeling of target loci.” Mol. Cell. Biol. 28: 815-828.PubMed

Chang, J. L., Lin, H. V., Blauwkamp, T. A. and Cadigan, K. M. (2008). “Spenito and Split ends act reduntantly to promote Wingless signaling.” Dev. Biol. 314: 100-111. PubMed

Li, J., Sutter, C., Parker, D.S., Blauwkamp, T., Fang, M and Cadigan, K. M. (2007). “CBP/p300 binding protein is a bimodal regulator of Wnt signaling.” EMBO Journal 26: 2284-94.PubMed

Guan, J., Li, H., Rogulja, A., Axelrod, J. and Cadigan, K. M. (2007). “The Drosophila Casein kinase Ie/d Discs overgrown promotes cell survival via activation of DIAP1 expression.”Developmental Biology 301: 16-28. PubMed

Parker, D. S., Blauwkamp, T, and Cadigan, K. M. (2007). “Wnt/beta-catenin-mediated transcriptional regulation.” In Wnt Signaling in Embryonic Development, Sokol S., (ed), Advances in Developmental Biology, Wassarman PM (ed) Vol. 17, pp. 1-61. San Diego: Elsevier..

Feng, Y., Bommer, G. T., Zhai, Y., Akyol, A., Hinoi, T., Winer, I., Lin, H. V., Cadigan, K. M., Cho, K. R. and Fearon, E. R. (2007). “Drosophila split ends Homologue SHARP Functions as a positive regulator of Wnt/b-catenin/TCF signaling in neoplastic transformation.” Cancer Res. 67:482-491. PubMed

Fang, M., Li, J., Blauwkamp, T., Bhambhani, C., Campbell, N. and Cadigan, K. M. (2006). “C-terminal binding protein directly activates and represses Wnt transcriptional targets in Drosophila.” EMBO Journal 25: 2735-2745. PubMed

Cadigan, K. M. and Liu, Y. I. (2006). “Wnt signaling: complexity at the surface.” Journal of Cell Science 119: 395-402. PubMed

Fearon, E. R. and Cadigan, K. M. (2005). “Wnt signaling glows with RNAi.” Science 308: 801-803.

Lin, H. V., Rogulja, A. and Cadigan, K. M. (2004). “Wingless signaling eliminates ommatidia from the edge of the developing eye through activation of apoptosis.” Development 131: 2409-2418 . PubMed