Elli M Buchert, Elizabeth A Fogarty, Christopher Uyehara, Daniel J McKay, Laura Buttitta* (2023) “A tissue dissociation method for ATAC-seq and CUT&RUN in Drosophila pupal tissues. In press at FLY.

Kenji Yumoto, Jibraan Rashid, Kristina G. Ibrahim, Steven P. Zielske, Yu Wang, Maiko Omi, Ann M. Decker, Younghun Jung, Dan Sun, Henriette A. Remmer, Yuji Mishina, Laura A. Buttitta, Russell S. Taichman, and Frank C. Cackowski (2023) “HER2 as a Potential Therapeutic Target on Quiescent Prostate Cancer Cells” Translational Oncology Feb 18;31:101642. doi: 10.1016/j.tranon.2023.101642

Graniel JV, Teitel J, Glineburg MR, Cohen E, Buttitta LA, Barolo S, Allen BL. Developing Future Biologists: developmental biology for undergraduates from underserved communities. Development. 2023 Jan 1;150(1):dev201337. doi: 10.1242/dev.201337

Nandakumar S, Buttitta L. Using Mosaic Cell Labeling to Visualize Polyploid Cells in the Drosophila Brain. Methods Mol Biol. 2023;2545:413-425. doi: 10.1007/978-1-0716-2561-3_22. PMID: 36720826.

Ajai J. Pulianmackal, Kiriaki Kanakousaki, Kerry A. Flegel, Olga Grushko, Ella Gourley, Emily Rozich and Laura A. Buttitta* “Mis-regulation of the Nucleoporins 98 and 96 leads to defects in protein synthesis that promote hallmarks of tumorigenesis.” Disease Models & Mechanisms 15 (3): dmm049234. doi.org/10.1242/dmm.049234
*Selected as an “Editor’s Choice” for the issue and cover feature: “The paradoxical role of nucleoporins in tumourigenesis” Dis Model Mech (2022) 15 (3): e15_e0301 **Nominated for DMM paper of 2022!

Ajai Pulianmackal, Dan Sun, Kenji Yumoto, Zhengda Li, Yu-Chih Chen, Meha Patel, Yu Wang, Euisik Yoon, Alexander Pearson, Qiong Yang, Russell Taichman, Frank Cackowski and Laura Buttitta* (2021) “Monitoring spontaneous quiescence and asynchronous proliferation-quiescence decisions in prostate cancer cells” Frontiers in Cell & Developmental Biology, Special Topic on Quiescence and Dormancy doi: 10.3389/fcell.2021.728663.

Allison M Box, Laura Buttitta* (2021) “Racing against the clock: How flies regenerate just in time” Invited Preview for Dev Cell available online July 26, 2021.

Shyama Nandakumar, Emily Rozich and Laura Buttitta* (2021) “Cell Cycle Re-entry in the nervous system: from polyploidy to neurodegeneration”. Front. Cell Dev. Biol. doi: 10.3389/fcell.2021.698661

Zhang AJ. Katzaroff, L. Buttitta, Y. Ma, H. Jiang, D. Nickerson J. Øvrebø and B. A. Edgar (2021) “The Krüppel-like-factor Cabut has cell cycle regulatory properties similar to E2F1” PNAS DOI: 10.1073/pnas.2015675118.

Younghun Jung, Frank C. Cackowski, Kenji Yumoto, Ann M. Decker, Yu Wang, Megan Hotchkin, Eunsohl Lee, Laura Buttitta, and Russell S. Taichman (2021) “Abscisic Acid Regulates Dormancy of Prostate Cancer Disseminated Tumor Cells in the Bone Marrow” Neoplasia Jan. vol 23 pp. 102-111

Shyama Nandakumar, Olga Grushko, Laura A. Buttitta “Polyploidy in the adult Drosophila brain” Elife. 2020 Aug 25;9:e54385. doi: 10.7554/eLife.54385.  * Reviewed in Faculty Opinions and Highlighted in The Scientist

Frank Cackowski, Yugang Wang, Joseph Decker, Christopher Sifuentes, Steven Weindorf, Younghun Jung, Yu Wang, Ann Decker, Kenji Yumoto, Nicholas Szerlip, Laura Buttitta, Kenneth Pienta, Todd Morgan, and Russell Taichman (2019) “Detection of Disseminated Tumor Cells in Bone Marrow of Patients with Clinically Localized Prostate Cancer” The Prostate vol. 79(14) pp. 1715-1727. doi: 10.1002/pros.23896

Yiqin Ma, Daniel J. McKay, Laura Buttitta (2019) “Changes in chromatin accessibility ensure robust cell cycle exit in terminally differentiated cells” PLOS Biology Sep 3;17(9):e3000378 doi: 10.1371/journal.pbio.3000378

Yiqin Ma and Laura Buttitta (2017) “Chromatin organization changes during the establishment and maintenance of the postmitotic state” Epigenetics & Chromatin Nov 10;10(1):53 doi: 10.1186/s13072-017-0159-8

Dan Sun and Laura Buttitta (2017) “States of G0 and the proliferation-quiescence decision in cells, tissues and during development” Review Article. International Journal of Developmental Biology

Uyehara CM, Nystrom SL, Niederhuber MJ, Leatham-Jensen M, Ma Y, Buttitta LA, McKay DJ. Hormone-dependent control of developmental timing through regulation of chromatin accessibility. Genes Dev. 2017 May 1;31(9):862-875. doi: 10.1101/gad.298182.117.

Guo Y, Flegel K, Kumar J, McKay DJ, Buttitta LA. Ecdysone signaling induces two phases of cell cycle exit in Drosophila cells. Biol Open. 2016 Nov 15;5(11):1648-1661. doi: 10.1242/bio.017525. PubMed PMID: 27737823

Flegel K, Grushko O, Bolin K, Griggs E, Buttitta L. The Role of the Histone Modifying and Exchange Complex NuA4 in Cell Cycle Progression in Drosophila melanogaster. Genetics. 2016 May 16. pii: genetics.116.188581. PMID: 27184390

Lee E, Decker AM, Cackowski FC, Kana LA, Yumoto K, Jung Y, Wang J, Buttitta L, Morgan TM, Taichman RS.Growth Arrest-Specific 6 (GAS6) Promotes Prostate Cancer Survival by G1 Arrest/S Phase Delay and Inhibition of Apoptotic Pathway During Chemotherapy in Bone Marrow.
J Cell Biochem. 2016 May 5. doi: 10.1002/jcb.25582. PMID: 27153245

Kelsey Bolin, Nicholas Rachmaninoff, Kea Moncada, Katharine Pula, Jennifer Kennell, Laura Buttitta (2016) “miR-8 modulates actin regulators to influence cell survival and compensatory proliferation” Developmental Biology Apr. 1 PMID: 26902111

Y. Jung, A.M. Decker, J. Wang, E. Lee, Lulia A. Kana, K. Yumoto, F.C. Cackowski, J. Rhee, P. Carmeliet, Laura Buttitta, T.M. Morgan, R.S. Taichman (2016) “Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow” Oncotarget Mar. 25 PMID: 27028863

Dan Sun and Laura Buttitta (2015) “Protein Phosphatase 2A promotes the transition to Gzero during terminal differentiation in Drosophila” Development Sept. 1, vol. 412, 3033-3045.

Ma Y, Kanakousaki K, Buttitta L (2015) How the cell cycle impacts chromatin architecture and influences cell fate. Frontiers in Genetics. 2015 Feb 3;6:19. doi: 10.3389

L. Buttitta and C.-Y. Lee (2014) Ch-Ch-Changes; Hormones link stem cell differentiation with metabolic flux. Cell Stem Cell vol. 15, 262-264

Kuang, K.L. Golden J. Damrath C.R. Simon L. Buttitta, C. Gamble, I.A. Dawson and C-Y. Lee (2014) “A novel Fizzy/Cdc20-dependent mechanism suppresses necrosis in neural stem cells” Development Mar 5. doi:10.1242/dev.104786.

D.D. O’Keefe, S. Thomas, B.A. Edgar, L. Buttitta (2014) “Temporal regulation of Dpp signaling outputs in the Drosophila wing” Developmental Dynamics Mar 2. doi: 10.1002/dvdy.24122.

M. Song, Y. Zhang, A. Katzaroff, B.A. Edgar and L. Buttitta (2014) “Hunting complex differential gene interaction patterns across molecular contexts” Nucleic Acids Research Jan. 29 PMID: 24482443.

Flegel, K., Sun, D., Grushko, O., Ma, Y., Buttitta, L. (2013). ” Live Cell Cycle Analysis Of Drosophila Tissues Using The Attune Acoustic Focusing Cytometer And Vybrant DyeCycle Violet DNA Stain.” J. Vis. Exp. e50239, doi:10.3791/50239.

O’Keefe DD, Thomas SR, Bolin K, Griggs E, Edgar BA, Buttitta LA (2012). ” Combinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters.” BMC Genomics, 13(1) p.498. PubMed

L. Buttitta, A.J. Katzaroff, B.A. Edgar. (2010). “A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo.” Journal of Cell Biology, vol. 189, 981-96.  PubMed

L. Buttitta and B.A. Edgar. (2007). “How size is controlled: From Hippos to Yorkies.” Nature Cell Biology, Vol. 9, 1225-1227. PubMed

L. Buttitta and B.A. Edgar. (2007). ” Mechanisms coordinating cell cycle exit and terminal differentiation.” Current Opinion in Cell Biology, Vol. 19, 697-704. PubMed

L. Buttitta, A.J. Katzaroff, C. Perez, A. De la Cruz, B.A. Edgar. (2007). “A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila.” Developmental Cell , Vol. 12, 631-643. PubMed