Michigan Tissue Barriers Biology Group – Molecular, Cellular, and Developmental Biology

Overcoming Barriers in Imaging:
a super-resolution microscopy workshop  

November 19-20, 2019

Kellogg Eye Center – Biological Sciences Building

This workshop will feature talks from two external super-resolution microscopy experts, presentations by the Managers/Directors of UM core microscopy facilities on key super-resolution microscopy techniques, talks from leaders of the Tissue Barriers Group, an interactive poster session, panel discussions, and opportunities for community building. Registration is free, but there are a limited number of seats, so you MUST pre-register to attend. Please contact Ann Miller with any questions: annlm@umich.edu

What are tissue barriers?

Understanding how cells connect to form tissue barriers is fundamental to understanding organ system function and developing effective treatment strategies for a wide range of debilitating diseases. Tissue barriers are generated by differentiation of cells to develop well-defined junctional complexes including adherens junctions, tight junctions, and desmosomes as well as communicating gap junctions.

Who are we?

The University of Michigan boasts a wide range of experts in the area of tissue barriers biology spread across multiple disciplines, departments, and colleges including the Medical School, Literature Science and the Arts, Pharmacy, and Engineering. The Tissue Barriers Group brings these researchers together to build on our common interest in understanding cell-cell junctions, which generate defined tissue environments and regulate growth and differentiation.

What does our group do?

A group of researchers and physician scientists investigating tissue barriers biology has been meeting routinely over the past several years to present new data, exchange ideas, and encourage collaboration and novel research strategies. The funding our Tissue Barriers Group received from the Biosciences Initiative provides an ideal opportunity to build upon our current strength in tissue barriers biology by organizing two workshops for our Tissue Barriers Group as well as other interested faculty, staff, and trainees. The workshops focus on two emerging areas of research that our labs could leverage to expand and strengthen our research programs:

  1. Using super-resolution microscopy for high resolution imaging of cell-cell junctions and their dynamics.
  2. Using induced pluripotent stem cells to create “organs on a dish” in order to model in vivo barriers and develop potential novel stem cell therapies.

These workshops will draw on local expertise and core facilities and also recruit internationally recognized leaders in these areas to share their knowledge with our community. 

Leadership Team for the Tissue Barriers Biosciences Initiative: 

Anuska Andjelkovic-Zochowska

MD, PhD (Associate Professor of Pathology; Research Associate Professor of Neurosurgery)

David Antonetti

PhD (Roger W. Kittendorf Research Professor of Ophthalmology and Visual Sciences; Professor of Molecular & Integrative Physiology)

Ann Miller

PhD (Associate Professor of Molecular, Cellular, and Developmental Biology)

Asma Nusrat

MD (F. Peyton Rous Professor and Director of Experimental Pathology in the Department of Pathology)

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