Publications

2024

Lucero RM, Demirer K, Yeh TJ, Stockbridge RB. (2024). Transport of metformin metabolites by guanidinium exporters of the small multidrug resistance family. J. Gen. Phys. 156: e202313464

Banerjee A, Kang C-Y, An M, Koff BB, Sunder S, Kumar A, Tenuta LMA, Stockbridge RB. (2024). Fluoride export is required for competitive fitness of pathogenic microorganisms in dental biofilm models. mBio:e00184-24.

2022

Martinez-Vaz BM, Dodge AG, Lucero RM, Stockbridge RB, Robinson AA, Tassoulas LJ, Wackett LP. (2022). Wastewater bacteria remediating the pharmaceutical metformin: Genomes, plasmids and productsFront. Bioengin. Biotech. 10:1086261.

Burata OE%, Yeh TJ%, Macdonald CB, Stockbridge RB. (2022). Still rocking in the structural era: a molecular overview of the Small Multidrug Resistance transporters. J. Biol. Chem. 298: 102482.

Kermani AA, Burata OE, Koff BB, Koide A, Koide S, Stockbridge RB. (2022). Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. eLife 11:e76766.

2021

McIlwain BM, Gundepudi R, Koff BB, Stockbridge RB. (2021). The fluoride permeation pathway and anion recognition in Fluc family fluoride channels. eLife 10e69482.

McIlwain BM, Ruprecht MT, Stockbridge RB. (2021). Membrane exporters of fluoride ion. Annual Review of Biochemistry. 90:559-579.

McIlwain BM, Erwin AL, Davis AR, Koff BB, Chang L, Bylund T, Chuang G-Y, Kwong PD, Ohi MD, Lai Y-T, Stockbridge RB. (2021). N-terminal transmembrane helix epitope tag for x-ray crystallography and electron microscopy of small membrane proteins. J. Mol. Biol. 433: 166909.

Stautz J, Hellmich Y, Fuss MF, Silberberg JM, Devlin JR, Stockbridge RB, Hänelt I. (2021). Molecular mechanisms for bacterial potassium homeostasis. J. Mol. Biol. 433:166968.

2016-2020

Kermani AA, Macdonald CB, Burata OE, Koff BB, Koide A, Denbaum E, Koide S, Stockbridge RB.  (2020).  Structural basis of promiscuity in Small Multidrug Resistance transporters.  Nat. Commun. 11:6064.

McIlwain BM, Martin K, Hayter EA, Stockbridge RB. (2020).  An interfacial sodium ion is an essential structural feature of Fluc family fluoride channels.  J. Mol. Biol. 432: 1098-1108.

Stull F, Hipp H, Stockbridge RB, Bardwell JCA. (2018).  In vivo chloride concentrations surge to proteotoxic levels during acid stress.  Nat. Chem. Biol. 14:1051-1058.  Find it here

Kermani A, Macdonald CB, Gundepudi R, Stockbridge RB (2018). Guanidinium export is the primal function of SMR family transporters. Proceedings of the National Academy of Sciences. 115: 3060-3065.  Learn about this exciting research!

McIlwain BC, Newstead S, Stockbridge RB. (2018) Cork-in-Bottle Occlusion of Fluoride Ion Channels by Crystallization Chaperones. Structure 26: 1-5. Find it here!

Macdonald CB, Stockbridge RB. (2017). A topologically diverse family of fluoride channels. Curr. Opin. Struct. Biol. 45:142-149. Read about it here!

Turman D, Stockbridge RB. (2017). Mechanism of single- and double-sided inhibition of dual topology fluoride channels by synthetic monobodies. J. Gen. Physiol. 149:511-522.This paper won the 2017 Paul F. Cranefield Award from the Society of General Physiologists! Find it here!  

Nelson JW, Athilo RM, Sherlock ME, Stockbridge RB, Breaker RR. (2017).  Metabolism of free guandine in bacteria is regulated by a widespread riboswitch class.  Molecular Cell.65: 1-11. Find it here

2011-2015

Stockbridge RB, Kolmakova-Partensky L, Shane T, Koide A, Koide S, Miller C, Newstead S. (2015). Crystal structures of a dual-topology, double-barrelled fluoride ion channel. Nature. 525:548-551. Learn about the structure in this article!

Stockbridge RB, Koide A, Miller C, Koide S. (2014). Proof of dual–topology architecture of Fluc F- channels with monobody blockers. Nat. Commun. 5:5120-5123. Read about monobodies here!

Ji C, Stockbridge RB, Miller C. (2014). Bacterial fluoride resistance, Fluc channels, and the weak acid accumulation effect. J. Gen. Physiol. 144:257-261. Go here to find out more!

Stockbridge RB, Robertson JL, Kolmakova-Partensky L, Miller C. (2013). A family of fluoride- specific ion channels with dual-topology architecture. eLife 2013;2:e01084. Read about the characterization of fluoride channels here!

Stockbridge RB, Lim H-H, Otten R, Williams C, Shane T, Weinberg Z, Miller C. (2012). Fluoride resistance and transport by riboswitch-controlled CLC antiporters. Proc. Natl. Acad. Sci. U.S.A. 109: 15289-15294. Read the article here!

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