Lab Members

Patricia (Trisha) Wittkopp : Principal Investigator

Patricia (Trisha) Wittkopp

Principal Investigator

Dr. Wittkopp's studies of evolution and development in Drosophila started during her undergraduate research with Dr. Greg Gibson at the University of Michigan (B.S. 1997), and continued during her doctoral work at the University of Wisconsin with Dr. Sean Carroll (Ph.D. 2002). From 2002-2005, Dr. Wittkopp studied the evolution of gene expression as a Damon Runyon Cancer Research Postdoctoral Fellow with Dr. Andy Clark at Cornell University. Coming full circle, the Wittkopp lab was officially founded at U. Michigan in August 2005.

Curriculum Vitae

wittkopp@umich.edu
Mark Hill : Post-doctoral Fellow

Mark Hill

Post-doctoral Fellow

Mark joined the Wittkopp Lab in November 2017 following the completion of his PhD at University College London, where, along with Dr Max Reuter, he characterised the genetic basis of sexual antagonism in Drosophila melanogaster, using a combination of experimental and computational approaches. In the Wittkopp lab, Mark will be exploring the evolution of gene regulation in budding yeast, Saccharomyces cerevisiae, primarily by combining experimental evolution and next generation sequencing.

Personal website: https://mark-stephen-hill.github.io/

marshill@umich.edu
Mo Siddiq : Post-doctoral Fellow

Mo Siddiq

Post-doctoral Fellow

Mo joined the lab in March 2019 after completing his PhD working with Joe Thornton in the Department of Ecology and Evolution at the University of Chicago. Mo’s dissertation research combined ancestral sequence reconstruction, protein biochemistry, and physiological assays of transgenic organisms to test hypotheses about the underlying genetic and functional mechanisms of alcohol adaptation in D. melanogaster. In the Wittkopp Lab, Mo will use natural and artificial variation in regulatory sequences to study how gene expression evolves, with a focus on experimentally characterizing how genotype-phenotype relationships shape and are shaped by long-term evolutionary divergence.

siddiqm@umich.edu
Abby Lamb : MCDB Graduate Student

Abby Lamb

MCDB Graduate Student

Abby earned her B.S. in Biology from University of Houston in 2012, where she studied speciation mechanisms in Drosophila pseudoobscura and D. persimilis. She started working in the Wittkopp lab in January 2014. Abby is currently researching the genetics underlying Drosophila pigmentation development and evolution. Her current research projects include investigating the genetic causes of body color divergence in D. americana and D. novamexicana, as well as the potential role of post-transcriptional regulation in the development of D. melanogaster pigmentation.

abbylamb@umich.edu
Petra Vande Zande : MCDB Graduate Student

Petra Vande Zande

MCDB Graduate Student

Petra graduated from Cornerstone University with a B.A. in Biology for Secondary Education in 2010, and taught high school biology for several years in Wisconsin previous to entering graduate school and joining the Wittkopp Lab in 2016. Petra’s research in the Wittkopp lab focuses on understanding the genome-wide impacts of regulatory mutations. In particular, she is interested in how changes in gene expression are propagated through cellular networks and ultimately impact cellular fitness.

pvzande@umich.edu
Henry Ertl : EEB Graduate Student

Henry Ertl

EEB Graduate Student

Henry earned his B.S. in Cell Biology and Genetics at the University of Maryland, College Park, where he studied the genetics of Drosophila speciation in the lab of Dr. Carlos Machado. After graduating, he joined Dr. Jan LaRocque's lab at Georgetown University as a lab technician focusing on DNA repair pathways in Drosophila. Henry joined the Wittkopp lab in fall 2017, and is interested in the mechanisms and evolution of developmental regulatory networks.

hertl@umich.edu
Tasmine Clement : MCDB Graduate Student

Tasmine Clement

MCDB Graduate Student

Tasmine received her B.S in Biological Sciences from the University of Notre Dame, where she studied rare disease progression. After graduating, Tasmine received an NIH grant to work under the supervision of Dr. Jake Tu at Virginia Tech to study genes involved in sex determination and early embryonic development. In October 2018, Tasmine joined the Wittkopp Lab as a master's student and is currently investigating miRNA-target interactions.

tasmine@umich.edu
Anna Redgrave : EEB Graduate Student

Anna Redgrave

EEB Graduate Student

Anna earned her bachelor's and master's in the lab of Dr. Ann Burke at Wesleyan University, contributing data from the zebrafish to a project comparing the embryonic origins of the vertebrate muscular body wall. She then worked for two years as a research technician in the lab of Dr. Sarah McMenamin studying the role of thyroid hormone signaling in zebrafish post-embryonic development. For her PhD in the Wittkopp lab, Anna is looking to zoom in on the molecular mechanisms of evolution, using computational techniques to study the evolution of gene regulatory networks. In her spare time, Anna enjoys farming, being near farms, and playing farm-themed video games.

Redgrave@umich.edu
Shadae Sutherland : MCDB PhD Candidate

Shadae Sutherland

MCDB PhD Candidate

Shadae joined the Wittkopp lab in March 2020 as an MCDB rotation PhD student. She is interested in studying gene regulation and will be using the yeast model system, Saccharomyces cerevisiae. to further explore it.

sssuther@umich.edu
Anati Azhar : UROP, Undergraduate Researcher

Anati Azhar

UROP, Undergraduate Researcher

Anati is an undergraduate student who started the Undergraduate Research Opportunity Program (UROP) in the Wittkopp Lab in her sophomore year, 2017. She assists Abby in her research project, which is examining the role of post-translational regulation in pigmentation evolution. Anati is specifically helping design tools for the detection of miRNA expression.

anati@umich.edu
Alicia Wang : Undergraduate Researcher

Alicia Wang

Undergraduate Researcher

Alicia is an undergraduate student majoring in Cellular and Molecular Biology with hopes of going to graduate school to pursue a career in research. She joined the Wittkopp lab in Winter 2019 and is working with Henry on further understanding the trans-acting aspect of genetics.

walicia@umich.edu
Nick Brown : Undergraduate Assistant

Nick Brown

Undergraduate Assistant

Nickbrow@umich.edu
Lisa Kim : Research Technician/Lab Manager

Lisa Kim

Research Technician/Lab Manager

Lisa graduated with her B.S. in Biology from the University of Michigan in 2016. She hopes to continue her research in the lab to understand how noise in gene expression affects fitness in yeast, while also applying to veterinary schools.

ligiki@umich.edu

Alumni