Bardwell Lab – Molecular, Cellular & Developmental Biology

James Bardwell’s lab uses directed evolution to improve protein folding. The researchers do this by asking organisms themselves to solve difficult protein-folding problems. By examining the solutions to these problems, the scientists are better able to understand folding in the cell.

This Quetzalcoatlus replica greets visitors to the University of Michigan’s Biological Sciences Building, the shared home of the the Bardwell Lab (Department of Molecular, Cellular & Developmental Biology) and the Museum of Natural History. The lab is located in beautiful Ann Arbor, MI, which has been rated the best city in the U.S. Read about Ann Arbor’s other rankings and accolades.

The Bardwell lab utilizes directed evolution; protein design; and a variety of cutting-edge structural, biological, and genetic approaches in the discovery and characterization of chaperones and to address human maladies, including phenylketonuria and nicotine dependence.  The lab is innovative, friendly, well-funded and safely operating in a COVID aware fashion.  

We currently can finance visitors to the lab at all levels: interns, grad students, postdoctoral fellows, and sabbatical scholars. Successful candidates will have been trained in directed evolution or structural biology or biochemistry or bacterial or yeast genetics.

If someone you know might be interested in coming for 4 months or more to a fun, productive lab in beautiful Ann Arbor, please have them contact me.  

Interested applicants should submit their CV to

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