

Kennedy Group Research
Welcome to the Kennedy Group homepage! Feel free to explore our website to develop a better understanding of our research projects and to obtain information about those working in the group.
As a bioanalytical chemistry lab, our goal is to develop analytical instrumentation and methods that can help solve problems of biological significance. The analytical techniques we investigate are based on microfluidics, chromatography, electrophoresis, mass spectrometry, and enzyme assays. These methods are applied to a variety of areas including endocrinology (e.g., understanding insulin secretion defects related to type 2 diabetes), neurochemistry (e.g., identifying neurochemical deficits associated with Huntington’s disease), and high-throughput screening for drug discovery and other applications.
In our work we must analyze complex mixtures, often at nanoliter volumes that contain only attomole or zeptomole quantities. These challenges create innumerable opportunities for analytical research. Students or post-docs with interest and skills in instrumentation, biology, analytical methods, organic chemistry, materials, and engineering can all contribute to the team.
Please follow the links to learn more about our projects related to analytical chemistry including lab-on-a chip, separations, and mass spectrometry and its applications in diabetes, neuroscience, and high-throughput screening.

Latest Publications
In depth chemical analysis of the brain extracellular space using in vivo microdialysis with liquid chromatography-tandem mass spectrometry.
Analytical Chemistry, 2024
Systematic evaluation of benzoylation for liquid chromatography-mass spectrometry analysis of different analyze classes.
Journal of Chromatography A, 2024
Preparation of high-efficiency HILIC capillary columns using slurry packing at 2,100 bar.
Journal of Chromatography A, 2024
High-throughput capillary liquid chromatography using a droplet injection and application to reaction screening.
Analytical Chemistry, 2024
Lab Blog: News and Events
- Yue Xin Data MeetingCongratulations to Yue on finishing her data meeting! She’s one step closer to earning her Ph.D.!
- Devin Makey GraduationCongratulations to Devin Makey for successfully defending his graduate thesis! Devin was working on improving separations using ion mobility and was co-advised by Bob and Brandon Ruotolo. We wish him luck as he begins work at Merck!
- Max Unger GatewayCongratulations to Max Unger for passing his gateway exam!
You must be logged in to post a comment.