Kennedy Group Research
Welcome to the Kennedy Group homepage! Feel free to explore our website to develop a better understanding of our research projects and to obtain information about those working in the group.
As a bioanalytical chemistry lab, our goal is to develop analytical instrumentation and methods that can help solve problems of biological significance. The analytical techniques we investigate are based on microfluidics, chromatography, electrophoresis, mass spectrometry, and enzyme assays. These methods are applied to a variety of areas including endocrinology (e.g., understanding insulin secretion defects related to type 2 diabetes), neurochemistry (e.g., identifying neurochemical deficits associated with Huntington’s disease), and high-throughput screening for drug discovery and other applications.
In our work we must analyze complex mixtures, often at nanoliter volumes that contain only attomole or zeptomole quantities. These challenges create innumerable opportunities for analytical research. Students or post-docs with interest and skills in instrumentation, biology, analytical methods, organic chemistry, materials, and engineering can all contribute to the team.
Please follow the links to learn more about our projects related to analytical chemistry including lab-on-a chip, separations, and mass spectrometry and its applications in diabetes, neuroscience, and high-throughput screening.
Latest Publications
Systematic evaluation of benzoylation for liquid chromatography-mass spectrometry analysis of different analyze classes.
Journal of Chromatography A, 2024
Preparation of high-efficiency HILIC capillary columns using slurry packing at 2,100 bar.
Journal of Chromatography A, 2024
High-throughput capillary liquid chromatography using a droplet injection and application to reaction screening.
Analytical Chemistry, 2024
High-throughput liquid chromatographic analysis using a segmented flow injector with a 1 s cycle time.
Analytical Chemistry, 2023
Lab Blog: News and Events
- Lab “Spotify Wrapped” 2021‘Tis the season for #SpotifyWrapped! Here are some groups and papers that inspired our grad students this year (in no particular order). Links to the papers are below •Castro, Nat Methods, 2021 •Fekete, J Chrom A, 2021 •Li, Nat Comm, 2020 •Schirmer, Anal Chem, 2020 •Xu, Anal Chem, 2021
- 2020 New StudentsWe are excited to announce that three new PhD students joined the Kennedy lab during the 2020-2021 academic year! Bridget Murray joins us from the University of Pittsburgh, and will be working on team high-throughput experimentation. Joe Naese joins us from Rowan University, where he worked with Kennedy lab alum Prof. Jim Grinias. Joe will… Read more: 2020 New Students
- NSF GRFP ResultsWe congratulate our group members for receiving offers and honorable mentions from the National Science Foundation Graduate Research Fellowship Program. Joshua Jones (incoming class of 2018) was awarded this prestigious fellowship for his proposed work in using liquid chromatography for the discovery of unique nucleosides. Josh performs this work between both the Kennedy and Koutmou groups. Additionally,… Read more: NSF GRFP Results
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