Current Projects

Study of Adolescent to Adult Neural Development (SAND): 1R01MH121079-01

Depression and anxiety are prevalent, debilitating, and poorly understood disorders. However, little is known about how adversity contributes to psychopathology. Thus, there is a critical need to rigorously conduct research with developmental samples from diverse backgrounds at increased risk for exposure to adversity and later psychopathology. We will assess 606 young adults (aged 20) from The Fragile Families and Child Wellbeing Study (FFCWS), an ongoing study of children born to predominantly low-income families. Attributes of the FFCWS are: 1) children were assessed at birth, 1, 3, 5, 9, 15 years; 2) the sample is representative of people born in cities and, thus, unlike almost all other neuroimaging research, findings are generalizable; 3) Although a full range of incomes are represented, there is substantial enrichment for low-income and African-American families, populations often under-represented in research; and 4) participants are entering early adulthood, a period of heightened risk for psychopathology. FFCWS participants currently live across the country in cities such as Detroit, Toledo, Chicago, Pittsburgh, and Indianapolis. We will bring these young adults to Ann Arbor to participate in an MRI session, psychiatric interviews, and self-reports, as well as provide biological samples. This study is funded by the National Institute of Mental Health (1R01MH121079-01; PIs: Christopher Monk) and is a collaboration with Luke Hyde, Colter Mitchell, and Nestor Lopez-Duran, at Michigan, as well as the FFCWS investigators.