Welcome to the Ledvina Lab!

Studying innate immune signaling in bacteria
MCDB Department, University of Michigan

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Our Research

Ubiquitin transferases

Incredible proteins conserved across the tree of life involved in regulating immune signaling

Phage defense pathways

These systems are incredibly diverse and employ unique and exciting biochemistry

Amyloid-mediate defense

Bacteria coat themselves in amyloid proteins to block invading predatory bacteria

New immune pathways

We explore the genetic diversity of bacteria to uncover novel components of the immune system

News

A person with short dark hair and glasses smiles for a selfie outdoors. They wear a black leather jacket and necklace, with blurred people and city buildings in the background.

Welcome Rachel!

Rachel has joined the lab as an MCDB PhD student investigating the role of E1/E2 domains in phage defense!

A young woman with long brown hair, wearing a textured pink sweater and a backpack, smiles outdoors in sunlight. Autumn leaves with shades of red and orange are visible in the background.

Welcome Katherine!

Katie has joined the lab as an MCDB PhD student studying the interaction of predatory bacteria and their prey!

Check it out!

The latest research from the lab was featured here!

October 2025

Kwame Kannatey-Asibu joins the team as a research technician!

The Ledvina Lab

University of Michigan
MCDB Department
Biological Sciences Building
Ann Arbor, Michigan

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