Welcome to the Ledvina Lab!

Studying innate immune signaling in bacteria
MCDB Department, University of Michigan

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Our Research

Ubiquitin transferases

Incredible proteins conserved across the tree of life involved in regulating immune signaling

Phage defense pathways

These systems are incredibly diverse and employ unique and exciting biochemistry

Amyloid-mediate defense

Bacteria coat themselves in amyloid proteins to block invading predatory bacteria

New immune pathways

We explore the genetic diversity of bacteria to uncover novel components of the immune system

News

Scientific figure from research articles displaying gene maps (A), a heatmap of phage fold protection (B), bar graphs of viral titer (C), gene arrangement diagrams (D), and 3D protein structure models (E–I).

Labs first paper!

Collaborative work led by Kanza in the lab was recently preprinted!

A smiling woman with dark hair wearing a maroon top.

Welcome Keerthikka!

Keerthikka has joined the lab as a postdoc studying defenses against predatory bacteria!

The Ledvina Lab

University of Michigan
MCDB Department
Biological Sciences Building
Ann Arbor, Michigan

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