Raven F, Vega Medina A, Schmidt K, He A, Vankampen AA, Balendran V, Aton SJ. (2025) Brief sleep disruption alters synaptic structures among hippocampal and neocortical somatostatin-expressing interneurons. SLEEP, , 48 (6) zsaf064, doi: 10.1093/sleep/zsaf064
Satchell M, Fry B, Noureddine Z, Simmons A, Ognjanovski NN, Aton SJ*, Zochowski M* (2025) Cholinergic modulation of neural networks supports sequential and complementary roles for NREM and REM states in memory consolidation. In Press, PLoS Computational Biology, doi.org/10.1371/journal.pcbi.1013097
Ognjanovski N, Kim DS, Charlett-Green E, van Koppen S, Aton SJ, Watson BO (2025) Daily rhythms drive dynamism in sleep, oscillations, and interneuron firing, while excitatory firing remains stable across 24-hours. European Journal of Neuroscience, (1):e16619. doi: 10.1111/ejn.16619
Aton SJ (2025) Melody for a memory: Sleep boosts the brain’s representation of sequential events. SLEEP, 48 (3) zsae316
Aton SJ (2024) Multi-omics as a strategy for understanding sleep’s role in memory. In press, Chapter in Genetics of Sleep and Sleep Disorders Gehrman P, Keene A, Grant S, eds.
Martinez JD, Wilson LG, Brancaleone WP, Peterson KG, Popke DS, Garzon VC, Perez Tremble RE, Donnelly MJ, Mendez Ortega SL, Torres D, Shaver JJ, Jiang S, Yang Z, Aton SJ. (2024) Hypnotic treatment improves sleep architecture and EEG disruptions and rescues memory deficits in a mouse model of Fragile X syndrome. Cell Reports. 43(6):114266. doi: 10.1016/j.celrep.2024.114266. .pdf Supplemental material.pdf
Wang L, Park L, Wu W, King D, Vega Medina A, Raven F, Martinez JD, Ensing A, McDonald K, Yang Z, Jiang S, Aton SJ. (2024) Sleep-dependent engram reactivation during hippocampal memory consolidation associated with subregion-specific biosynthetic changes. iScience. 27(4):109408. doi: 10.1016/j.isci.2024.109408. .pdf. Supplemental material.pdf
Martinez JD, Donnelly MJ, Popke DS, Torres D, Wilson LG, Brancaleone WP, Sheskey S, Lin C, Clawson BC, Jiang S, Aton SJ. (2023) Enriched binocular experience followed by sleep optimally restores binocular visual cortical responses in a mouse model of amblyopia. Communications Biology 6(1):408. doi: 10.1038/s42003-023-04798-y .pdf Supplemental material.pdf
Martinez JD, Brancaleone WP, Peterson KG, Wilson LG, Aton SJ (2023) Atypical hypnotic compound ML297 restores sleep architecture immediately following emotionally valenced learning, to promote memory consolidation and hippocampal network activation during recall. Sleep, 46(3):zsac301. doi: 10.1093/sleep/zsac301 .pdf Supplemental material.pdf
Wang L, Aton SJ (2022) Perspective – Ultrastructural analyses reflect the effects of sleep and sleep loss on neuronal cell biology. Sleep, 45(5): zsac047. doi: 10.1093/sleep/zsac047 .pdf
Delorme J, Wang L, Kodoth V, Wang Y, Ma J, Jiang S, Aton SJ (2021) Hippocampal neurons’ cytosolic and membrane-bound ribosomal mRNA profiles are differentially regulated by learning and subsequent sleep. Proceedings of the National Academy of Sciences, .pdf Supplemental material.pdf
Raven F, Aton SJ (2021) The engram’s dark horse: how interneurons regulate state-dependent memory processing and plasticity. Frontiers in Neural Circuits, 15:750541. doi: 10.3389/fncir.2021.750541 .pdf
Skilling Q, Eniwaye B, Clawson BC, Shaver J, Ognjanovski N, Aton SJ, Zochowski M (2021) Acetylcholine-gated current translates wake neuronal firing rate information into a spike timing-based code in non-REM sleep, stabilizing neural network dynamics during memory consolidation. PLoS Computational Biology, 17(9):e1009424 .pdf
Czarnecki P, Lin J, Aton SJ, Zochowski M (2021) Dynamical mechanisms underlying scale-free network reorganization in low acetylcholine states corresponding to slow wave sleep. Frontiers in Network Physiology,10.3389/fnetp.2021.759131 .pdf
Delorme J, Wang L, Kuhn FR, Kodoth V, Ma J, Martinez JD, Raven F, Toth BA, Balendran V, Vega Medina A, Jiang S, Aton SJ (2021) Sleep loss drives acetylcholine- and somatostatin interneuron-mediated gating of hippocampal activity, to inhibit memory consolidation. Proceedings of the National Academy of Sciences, . .df Supplemental material.pdf
Yang Y, Gritton H, Sarter M, Aton SJ, Booth V, Zochowski M (2021) Theta-gamma coupling emerges from spatially heterogeneous cholinergic neuromodulation. PLoS Comput Biol 17(7): e1009235. https://doi.org/10.1371/journal.pcbi.100923 .pdf
Aton SJ (2021) Aligning one’s sights: The pulvinar provides context for visual information processing. Neuron, 109 (12): 1909-1911 .pdf
Puentes-Mestril C, Delorme J, Donnelly M, Popke D, Jiang S, Aton SJ (2021) Sleep loss drives brain region- and cell type-specific alterations in ribosome-associated transcripts involved in synaptic plasticity and cellular timekeeping. Journal of Neuroscience, 41(25): 5386-98. DOI: 10.1101/2020.07.20.212019 .pdf
Clawson BC, Pickup EJ, Enseng A, Geneseo L, Shaver J, Gonzalez-Amoretti J, Zhao M, York K, Kuhn FR, Swift K, Martinez JD, Wang L, Jiang S, Aton SJ. (2021) Causal role for sleep-dependent reactivation of learning-activated sensory ensembles for fear memory consolidation. Nature Communications, 12: 1200. https://doi.org/10.1038/s41467-021-21471-2 .pdf
Bolsius Y, Zurbriggen MD, Kim JK, Kas MJ, Meerlo P, Aton SJ, Havekes R (2021) The role of clock genes in sleep, stress, and memory. Biochemical Pharmacology, 114493
Havekes R, Aton SJ (2020) Impacts of sleep loss versus waking experience on brain plasticity: Parallel or orthogonal? Trends in Neuroscience, 43(6):385-393 DOI: 10.1016/j.tins.2020.03.010. pdf
Wu J, Aton SJ, Booth V, Zochowski M (2020) Network and cellular mechanisms underlying heterogenous excitatory/inhibitory balanced states. European Journal of Neuroscience, 51(7): 1624-41. DOI: 10.1111/ejn.14669 .pdf
Skilling Q, Ognjanovski N, Aton SJ, Zochowski M (2019) Critical dynamics mediate learning of new distributed memory representations in neuronal networks. Entropy, 21: 1043. DOI:10.3390/e21111043 .pdf
Durkin JM, Aton SJ (2019) How sleep shapes thalamocortical circuit function in the visual system. Annual Review of Vision Science, 5:16.1-21, DOI: 10.1146/annurev-vision-091718-014715 .pdf
O’Malley HA, Hull JM, Clawson BC, Chen C, Owens-Fiestan G, Jameson MB, Aton SJ, Parent JM, Isom LL (2019) Scn1b deletion in adult mice results in seizures and SUDEP. Annals of Clinical and Translational Neurology, 6: 1121–1126. DOI: 10.1002/can3.785 .pdf
Puentes-Mestril C, Roach J, Niethard N, Zochowski M, Aton SJ (2019) How rhythms of the sleeping brain tune memory and synaptic plasticity. SLEEP, zsz095, DOI:10.1093/sleep/zsz095 .pdf
Delorme J, Kodoth V, Aton SJ (2019) Sleep loss disrupts Arc expression in dentate gyrus neurons. Neurobiology of Learning and Memory, pii: S1074-7427(18)30091-1. doi: 10.1016/j.nlm.2018.04.006 .pdf
Clawson BC, Durkin J, Suresh AK, Pickup EJ, Broussard C, Aton SJ (2018) Sleep promotes, and sleep loss inhibits, selective changes in firing rate, response properties, and functional connectivity of primary visual cortex neurons. Frontiers in Systems Neuroscience, 12: 40. DOI: 3389/fnsys.2018.00040 .pdf
Ognjanovski N, Broussard C, Zochowski M, Aton SJ (2018) Hippocampal network oscillations drive memory consolidation in the absence of sleep. Cerebral Cortex, 1-13. doi: 10.1093/cercor/bhy174 .pdf
Roach JP, Pidde O, Katz E, Wu J, Ognjanovski N, Aton SJ, Zochowski M (2018) Resonance with subthreshold oscillatory drive organizes activity and optimizes learning in neural networks. Proceedings of the National Academy of Sciences, DOI: 10.1073/pnas.1716933115 .pdf
Wu J, Skilling Q, Maruyama D, Li C, Ognjanovski N, Aton SJ, Zochowski M (2018) Functional Network Stability and Average Minimal Distance – A framework to rapidly assess dynamics of functional network representations. Journal of Neuroscience Methods, 296: 69-83, DOI: 10.1016/j.jneumeth.2017.12.021 .pdf
Durkin JM, Suresh A, Colbath J, Broussard C, Wu J, Zochowski M, Aton SJ (2017) Thalamocortical oscillations in NREM sleep play an essential, instructive role in visual system plasticity. Proceedings of the National Academy of Sciences, 114:10485-10490 DOI: 10.1073/pnas.1710613114 .pdf
Puentes-Mestril C, Aton SJ (2017) Linking network activity to synaptic plasticity during sleep: hypotheses and recent data. Frontiers in Neural Circuits, 11(61): DOI: 10.3389/fncir.2017.00061 .pdf
Ognjanovski N, Schaeffer S, Mofakham S, Wu X, Maruyama D, Zochowski M, Aton SJ (2017) Parvalbumin-expressing interneurons coordinate hippocampal network dynamics required for memory consolidation. Nature Communications, 8:15039: DOI: 10.1038/ncomms15039 .pdf
Havekes R, Park AJ, Ferri SL, Tudor JC, Bruinenberg V, Poplawski SG, Day JP, Aton SJ, Radwańska K, Meerlo P, Houslay MD, Baillie GS, Abel T (2016) Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. eLife 10.7554/eLife.13424 .pdf
Clawson B, Durkin J, Aton SJ (2016) Form and function of sleep spindles across the lifespan. Neural Plasticity, 2016: Article ID 6936381 .pdf
Durkin JM, Aton SJ (2016) Sleep-dependent potentiation in the visual system is at odds with the Synaptic Homeostasis Hypothesis. SLEEP, 39(1):155–9. .pdf
Gerstner JR, Aton SJ, Heller HC (2015) Waking up to the alarm: Sleep, clocks, and making memory (s)tick. Frontiers in Systems Neuroscience, 9: 65. .pdf
Bridi MCD, Aton SJ, Seibt J, Renouard L, Coleman T, Frank MG (2015) Rapid eye movement sleep promotes cortical plasticity in the developing cat. Science Advances, 1(6):e1500105. .pdf
Ognjanovski N, Maruyama D, Lashner N, Zochowski M, Aton SJ (2014) CA1 hippocampal network activity changes during sleep-dependent memory consolidation. Frontiers in Systems Neuroscience, 8: 61. .pdf
Aton SJ, Suresh A, Broussard C, Frank MG (2014) Sleep promotes cortical response potentiation following visual experience. SLEEP, 37(7):1163-70. .pdf
Prince TM, Choi J, Wimmer M, Havekes R, Aton S, Abel T (2014) Sleep deprivation during a specific 3-hour time window post-training impairs hippocampal synaptic plasticity and memory. Neurobiology of Learning and Memory, 109: 122-30. .pdf
Dumoulin M, Aton SJ, Watson A, Coleman T, Frank MG (2013) Extracellular signal-regulated kinase (ERK) activity during sleep consolidates cortical plasticity in vivo. Cerebral Cortex, 25(2):507-15. .pdf
Freeman GM Jr, Krock RM, Aton SJ, Thaben P, Herzog ED. (2013). GABA Networks Destabilize Genetic Oscillations in the Circadian Pacemaker. Neuron, 78(5):799-806. .pdf
Aton SJ. (2013). Set and setting: How behavioral state regulates sensory function and plasticity. Neurobiology of Learning and Memory, 106: 1-10. .pdf
Aton SJ, Broussard C, Dumoulin M, Seibt J, Watson A, Coleman T, Frank MG. (2013). Visual experience and subsequent sleep induce sequential plastic changes in putative inhibitory and excitatory cortical neurons. Proceedings of the National Academy of Sciences, 110(8):3101-6. .pdf
Frank M, Waldrop R, Dumoulin M, Aton SJ, Boal JG . (2012). Sleep-like states in the cuttlefish Sepia officinalis. PLoS ONE, 7(6):e38125. .pdf
Seibt J, Dumoulin M, Aton SJ, Coleman T, Watson A, Naidoo N, Frank MG. (2012). Protein synthesis during sleep consolidates cortical plasticity in vivo. Current Biology, 22(8):676-82. .pdf
Aton SJ, Seibt J, Dumoulin M, Coleman T, Shiraishi M, Frank MG. (2009). The sedating antidepressant trazodone impairs sleep-dependent cortical plasticity. PLoS ONE, 4(7): e6078. .pdf
Aton SJ, Seibt J, Dumoulin M, Jha SK, Steinmetz N, Coleman T, Naidoo N, Frank MG. (2009). Mechanisms of sleep-dependent consolidation of cortical plasticity. Neuron, 61(3): 454–466. .pdf
Aton SJ, Seibt J, Frank MG. (2009). Sleep and memory. Encyclopedia of Life Sciences, John Wiley & Sons, Ltd: Chichester. .pdf
Uebele VN, Nuss CE, Santarelli VP, Garson SL, Kraus RL, Stauffer SR, Barrow JC, Koblan KS, Renger JJ, Aton S, Seibt J, Dumoulin M, Jha SK, Coleman T, Frank MG. (2009). T-type calcium channels regulate cortical plasticity in vivo. NeuroReport, 20(3): 257–262. .pdf
Seibt J, Aton SJ, Jha SK, Coleman T, Dumoulin MC, Frank MG. (2008). The non-benzodiazepine hypnotic Zolpidem impairs sleep-dependent cortical plasticity. SLEEP, 31(10): 1381-91. .pdf
Saxena MT, Aton SJ, Hildebolt C, Prior J, Abraham U, Piwnica-Worms D, Herzog ED. (2007). Bioluminescence imaging of Period1 gene expression in utero. Molecular Imaging, 6(1): 68-72. .pdf
Aton SJ, Huettner JE, Straume M, Herzog ED. (2006). GABA and Gi/o differentially control circadian rhythms and synchrony in clock neurons. Proceedings of the National Academy of Sciences, 103(50): 19188-93. .pdf
Aton SJ, Herzog ED. (2005). Come together, right… now: Synchronization of rhythms in a mammalian circadian clock. Neuron, 48(4): 531-4. .pdf
Aton SJ, Colwell CS, Harmar AJ, Waschek J, Herzog ED. (2005). Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons. Nature Neuroscience, 8(4): 476-83 . .pdf
Aton SJ, Block GD, Tei H, Yamazaki S, Herzog ED. (2004). Plasticity of circadian behavior and the suprachiasmatic nucleus following exposure to non-24 hour light cycles. Journal of Biological Rhythms, 19(3): 198-207. .pdf
Herzog ED, Aton SJ, Numano R, Sakaki Y, & Tei H. (2004). Temporal precision in the mammalian circadian system: a reliable clock from less reliable neurons. Journal of Biological Rhythms, 19(1): 35-46. .pdf
Granados-Fuentes D, Saxena MT, Prolo LM, Aton SJ, Herzog ED. (2004). Olfactory bulb neurons express functional, entrainable circadian rhythms. European Journal of Neuroscience, 19(4): 898-906. .pdf