The Bridwell-Rabb lab uses a combination of X-ray crystallography, enzymology, biophysical methods, and biochemical approaches to study how microbes engineer and modify light-dependent processes. Our goals are to investigate how the photosynthetic pigments chlorophyll and bacteriochlorophyll are modified in the presence and absence of oxygen to absorb a broader range of light (Project 1), how enzymes use a common set of metallocenters to perform one, two, or three hydroxylation reactions (Project 2), and how light-dependent gene regulation is accomplished (Project 3).
please explore more about our research projects below
Tailor the photosynthetic pigments chlorophyll and bacteriochlorophyll to extend the usable range of photosynthetic light.
Understand how Rieske oxygenases are structurally programmed to differentiate between catalyzing reactions with diverse outcomes.
Translate environmental light conditions into a response.