Lab Members

Matthew Chapman : Principle Investigator

Matthew Chapman

Principle Investigator

chapmanm@umich.edu

Ph.D. Microbiology, Indiana University
Keck and NIH Fellow, Hultgren Lab, Washington University

Matt joined the MCDB faculty in September of 2003 after a post doc at Washington University in St. Louis. He did his graduate work at Indiana University where he studied RNA-dependent RNA replication. It was there that Matt became interested in the host-pathogen interaction and so he joined Scott Hultgren's lab at Washington University in order to study urinary tract infections. However, he quickly discovered that bacterial amyloid fiber formation and function were far more interesting and his group has worked on functional amyloids ever since.

His wife and two children keep him busy when he is out of the lab.

Kanna Nagamatsu : Research Laboratory Specialist Intermediate

Kanna Nagamatsu

Research Laboratory Specialist Intermediate

nkanna@umich.edu

M.S. University of Tokyo, Japan
Ph.D. University of Tokyo, Japan

Kanna joined the Chapman lab as a staff scientist in November 2016.

She spent 6 years studying interactions between uropathogenic Escherichia coli and host immune responses in Dr. Scott Hultgren's lab at Washington University in St. Louis School of Medicine.

Her current research is focused on bacterial amyloid (Curli) biogenesis to determine how and when curli are assembled.

She loves birds, especially her parrot, Mugi. Kanna also enjoys watching and playing tennis. She has been to NYC and watched the US Open Tennis in person many times.

Hema Swasthi : Post-Doc

Hema Swasthi

Post-Doc

hswas@umich.edu

M.S. Pondicherry University, India
Ph.D. Indian Institute of Science Education and Research, Mohali (IISER Mohali), India

Hema joined the Chapman lab as a postdoc in November 2018 after completing PhD with Prof. Samrat Mukhopadhyay. She is interested in understanding the spatiotemporal regulation of curli assembly on the bacterial surface.

Janet Price : Graduate Student Researcher

Janet Price

Graduate Student Researcher

janetep@umich.edu

B.S. Central Michigan University
M.S. Central Michigan University

Janet is interested in the overall process by which cells sense, internalize, and transduce environmental cues to initiate biofilm formation. Her project focuses on oxygen availability and redox state dependent affects on extracellular matrix component production.

When Janet has the time, she can be found playing videogames, reading over a cup of tea, or amassing her beloved shoe collection.

Sujeet Bhoite : Graduate Student Researcher

Sujeet Bhoite

Graduate Student Researcher

sbhoite@umich.edu

B.S. University of Pune
M.S. Hislop School of Biotechnology

Sujeet is interested in studying the role of human microbiome in neurodegenerative diseases like Parkinson’s disease. His project involves studying the impact of microbial amyloids on human amyloid forming proteins, like α-synuclein.
Sujeet is an astrophile and loves reading about theoretical physics and likes playing snooker in his free time.

Elizabeth Gichana : Graduate Student Researcher

Elizabeth Gichana

Graduate Student Researcher

egichana@umich.edu

We are excited that Elizabeth has chosen the Chapman lab! Elizabeth is a Biophysics student with a strong background in molecular simulations. She is currently working on chemical modulators of amyloid formation.

Anthony Balistreri : Graduate Student Researcher

Anthony Balistreri

Graduate Student Researcher

abalist@umich.edu

B.S. Santa Clara University
M.S. San Jose State University

Anthony is part of Michigan's Program in Chemical Biology and  joined the Chapman Lab in 2017. He is interested in exploring the possible therapeutic benefits to the anti-amyloid protein CsgC and how interfering with curli production can affect the microbiome.

In his spare time Anthony can be found in a kitchen somewhere, making something delicious for his friends.

Nana Yaa Britwum : Pathways Masters Student

Nana Yaa Britwum

Pathways Masters Student

nanabrit@umich.edu

B.S. Dual Major in Plant Science and Agricultural Science, Cornell University

Nana is an MCDB pathways M.S. student and a Rackham Merit Fellow. Her project focuses on making fluorescently tagged CsgG pore in order to use high-resolution fluorescence microscopy to elucidate the role CsgG plays in curli biogenesis. Her hobbies include cooking and exploring Michigan.

Mark Gomulinski : Lab Technician

Mark Gomulinski

Lab Technician

gomulins@umich.edu

B.S. Michigan State University

Mark joined the lab as a research technician in early 2018. Working with Hakam, his efforts focus on testing novel compounds against amyloid cross seeding and fiber formation.

Alexandra (Alex) Christensen : Undergraduate Researcher

Alexandra (Alex) Christensen

Undergraduate Researcher

alexhc@umich.edu

Alex is an undergraduate in the Chapman lab assisting Elizabeth on projects investigating the effects of both synthetic compounds and various types of growth media on bacterial biofilm formation.

Rachel Alessio : Undergraduate Researcher

Rachel Alessio

Undergraduate Researcher

ralessio@umich.edu

Rachel is studying Neuroscience on the pre-med track. She is working closely with Anthony on cloning and purifying CsgC homologs to test their activity against CsgA proteins of varying amyloid formation kinetics. Their project hopes to fine tune the CsgC protein's general efficiency in preventing amyloid formation, as well as gear its activity toward inhibiting non-native, human client proteins.

Isaac Payne : Undergraduate Researcher

Isaac Payne

Undergraduate Researcher

isaacp@umich.edu

Isaac is a Biochemistry major working with Elizabeth. His project works on identifying small molecules that inhibit the formation of amyloids by the proteins CsgA and alpha synuclein. While classes leave little time for anything else, Isaac is an avid athlete and enjoys soccer with friends.

Sania Farooq : Undergraduate Researcher

Sania Farooq

Undergraduate Researcher

sffarooq@umich.edu

Sania is a major in Public Health Science working closely with Kanna. Her project focuses on labeling the curli biogenesis proteins to be able to see how, where, and when curli are assembled. When she's not in lab, she is creating and capturing stunning narratives through her photography.

Emily Bozich : Work Study Student

Emily Bozich

Work Study Student

ebozich@umich.edu

Emily is studying Biomedical Engineering with a minor in Spanish. She is involved in Dance Marathon, M-HEAL, and student ambassadors on campus.