Principal Investigator – Infection Prevention in Aging

Principal Investigator

Lona Mody, MD, M.Sc

Dr. Mody is Amanda Sanford Hickey Professor of Internal Medicine and directs the Center for Research and Innovations in Special Populations (CRIISP). She is a tenured professor at Michigan Medicine and VA Ann Arbor Healthcare System.

Funded by NIA, AHRQ, UM Pepper Center, CDC, VA and Foundations, her research defines the clinical and molecular epidemiology of antimicrobial resistant pathogens and develop novel interventions to prevent them. In order to achieve her goals, she collaborates with investigators across the translational spectrum and disciplines, including infectious diseases, hospital medicine, molecular epidemiology, health outcomes researchers, nursing and health policy.

In an NIH-R01 randomized controlled study, her team evaluated a multi-modal targeted infection-prevention (TIP) intervention to prevent resistant organisms and infections in post-acute and long-term care residents with indwelling devices. This innovative work led to a successful AHRQ contract to implement our intervention in over 500 facilities across 50 states in the US. Funded by another NIH-R01, she defined the complex relationship between antimicrobial resistance, functional disability and the role of regional networks in transmission of resistant pathogens and developed interventions to disrupt this transmission. In another study, funded by the VA CSR&D Merit Review, she studies transmission of drug resistant organisms in common use areas by hospitalized patients and downstream consequences of these events.

Her most recent funding – Revolutionizing Precision Health Among Older Adults involving the UM and two academic institutions in Israel will address major challenges related to healthy aging including understanding and preventing common recurring infections that decrease quality and quantity of life. Funded by NIA, she has led many clinical, research and training initiatives during COVID-19 Pandemic with an explicit focus on older adults.

She directs her division’s T32 training grant and with support from NIA K24 is actively involved in mentoring the next generation of physician-scientists. She and her mentees have published in high impact journals such as JAMA, JAMA Internal Medicine, Clinical Infectious Diseases, J of American Geriatrics Society and PNAS. She has published several career development articles particularly on work-life balance.

CV Link

In the news:


September 15, 2019 Inverse: Human-Fueled Superbugs Are Putting This Intelligent Animal in Dang

July 2019 ACP Hospitalist: Patient and physician hygiene go hand in hand

April 2019 UofMHealth: ‘Superbugs’ Found on Patients’ Hands and What They Touch

April 2019 University of Michigan IHPI: The fight against ‘superbugs’ in hospitals has a new battlefield: patients’ hands and high-touch objects

April 16, 2019 Infection Control Today: Superbugs Found on Many Hospital Patients’ Hands and What They Touch Most Often

April 15, 2019 University of Minnesota CIDRAP: Study finds drug-resistant pathogens fairly common on patients’ hands

April 15, 2019 New York Post: ‘Superbug’ germs found all over hospital patients’ hands: study

April 15, 2019 Fox News: ‘Superbug’ germs found all over hospital patients’ hands: study

April 15, 2019 MSN: Hospital Patients Are Spreading Superbugs

April 15, 2019 Becker’s Healthcare: 14% of new hospital patients harbor superbugs: 4 study findings

April 14, 2019 ScienceDaily: ‘Superbugs’ found on many hospital patients’ hands and what they touch most often

April 2019 The Guardian: Curtains in patients’ rooms often rife with drug-resistant germs – study

April 12, 2019 The Straits Times: Privacy curtains at hospitals could be reservoir of deadly bacteria: Study

April 12, 2019 ABS CBN News: Privacy curtains could be reservoir of deadly bacteria: study

April 11, 2019 CTV News: Hospital privacy curtains harbour antibiotic-resistant germs: study

September 12, 2017 ScienceDaily: ‘Superbug’ bacteria gang up on us, fueled by antibiotic use, nursing home study suggests

May 24, 2017 Healio: Multi-faceted approach reduces CAUTIs among nursing home patients

May 22, 2017 Infection Control Today: Study shows 54 percent drop in CAUTIs among nursing home residents

May 19, 2017 Medical Xpress: Nursing homes cut urinary tract infections in half through focused effort on catheter care

October 6, 2016 Infection Control Today: U-M researchers to study role of patients’ hands as key factors in the spread of superbugs

October 6, 2016 UMHS News: CDC taps Mody and other U-M researchers for major effort to fight “superbug” bacteria through research

October 6, 2016 IHPI: CDC taps Mody and other U-M researchers for major effort to fight “superbug” bacteria

June 23, 2016 Health Standards: Balancing infection control and patient engagement

June 16, 2016 Newsmax Health: 1 in 3 seniors leave hospital with superbug

May 11, 2016 Issues of the environment: fighting superbugs and hospital infections

April 13, 2016 Pharmacy Times: 3 simple ways pharmacists can prevent superbug spread

April 5, 2016 How to control infection rates in the elderly after a hospital stay

March 18, 2016 Legal Reader: Patients leave hospitals carrying superbugs on their hands

March 17, 2016 1 in 4 seniors have superbugs on hands after hospital stay

March 17, 2016 Tech Times: 1 in 4 seniors leave hospital with superbugs on their hands

March 16, 2016 Nephrology News & Issues: Patients often carry multidrug-resistant organisms on their hands

March 16, 2016 Kaiser Health News: It’s not just doctors and nurses, patients need to wash their hands, too

March 15, 2016 Science Daily: 1 in 4 seniors have superbugs on their hands after a hospital stay, new research finds

March 14, 2016 Health Day: Seniors often bring drug-resistant germs to rehab centers

February 11, 2016 Reader’s Digest: UTI causes: surprising reasons you’re getting urinary tract infections out of nowhere

July 7, 2015 Healio: Targeted infection program decreases MRSA, UTI transmission in nursing homes

July 1, 2015 Reuters: Overuse of nursing home antibiotics may put all residents at risk

June 29, 2015 MedPage Today: Overused antibiotics cause havoc among nursing home patients

May 28, 2015 Science Daily: High rates of MRSA transmission found between nursing home residents, healthcare workers

March 20, 2015 Michigan Radio: Study shows simple measures reduce infections in nursing homes

March 18, 2015 UMHS News: Could simple measures tip the balance against antimicrobial resistance in nursing homes?

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