At U of M (09/2016-present)^: corresponding author, *: equal contribution, __: Undergraduate students, Blue: Graduate students
- Fang S, Chen G, Wang Y, Ganti R, Chernova TA, Zhou L, Jacobs SE, Duong D, Kiyokawa H, Chernoff YO, Li M, Shcherbik N, Zhao B, Yin J.^ (2023) Profiling and verifying the substrates of E3 ubiquitin ligase Rsp5 in yeast cells. STAR Protoc. 2023 Aug 9;4(3):102489.
- FM Arines, A Wielenga, OE Burata, FN Garcia, RB Stockbridge, Li M.^(2023) Lysosome transporter purification and reconstitution identifies Ypq1 as a pH-gated lysine transporter. MBoC, Accepted
- Venkatarangan V., Zhang W., Yang X., Thoene J., Hahn S., Li M.^(2023) ER-associated degradation in cystinosis pathogenesis and the prospects of precision medicine. J Clin. Invest., In press, News Release: https://news.umich.edu/rare-disease-shares-mechanism-with-cystic-fibrosis/
- Zhang B., Yang X., Li M.^ (2023) LYSET/TMEM251/GCAF is critical for autophagy and lysosomal function by regulating the mannose-6-phosphate (M6P) pathway. Autophagy doi: 10.1080/15548627.2023.2167375. Written by an awesome undergrad Bokai Zhang
- Zhang W*., Yang X*., Li Y., Yu L., Zhang B., Zhang J., Cho W., Venkatarangan V., Chen L., Burugula B., Bui S., Wang Y., Duan C., Kitzman J. and Li M.^ (2022) GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway. Nature Comm., 13(1):5351. PMCID: PMC9468337, Featured by “Editors’ Highlights“, recommended by Faculty Opinions, and reported by many news channels. https://news.umich.edu/missing-pathway-in-lysosome-underlies-newly-discovered-human-disease/ https://www.nature.com/articles/s41467-022-33025-1/metrics
- Arines F.M^. and Li M^. (2022) An optimized protocol to analyze membrane protein degradation in yeast using quantitative Western blot and flow cytometry. STAR Protocols. In press
- Zhang W., Yang X., Chen L., Liu Y., Venkatarangan V., Reist L., Hanson P., Xu H., Wang Y., and Li M.^ (2021) A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins. PLOS Biology. 19(7): e3001361. PMCID: PMC8337054
- Yang X., Reist L*., Chomchai D*., Chen L., Arines F.M., and Li M^. (2021) ESCRTs, not intralumenal structures, are important for the degradation of vacuole membrane and plasma membrane transporters. J Cell Biol. 220(8) Highlighted by a Spotlight article.
- Wang Y., Fang S., Chen G., Ganti R., Chernova T., Zhou L., Duong D., Kiyokawa H., Li M., Zhao B., Shcherbik N.,Chernoff Y., Yin J. (2021) Regulation of the endocytosis and prion-chaperoning machineries by yeast E3 ubiquitin ligase Rsp5 as revealed by orthogonal ubiquitin transfer. Cell Chemical Biol. In press
- Arines F.M., Hamlin A., Yang X., Liu Y., and Li M^. (2021) A selective transmembrane recognition mechanism by a membrane-anchored ubiquitin ligase adaptor. J Cell Biol. 220(1) Highlighted by a Spotlight article
- Yang X*., Zhang W*., Wen X., Bulinski PJ, Chomchai D., Arines F., Liu Y., Sprenger S., Teis D., Klionsky D., and Li M^.(2020) TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy J. Cell Biol. 219(3) Recommended by Faculty Opinions
- Suzuki SW*, Chuang YS*, Li M., Seaman MNJ, and Emr SD.(2019) A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling, J. Cell Biol. 218(9) 2876-2886
- Yang X., Arines FM., Zhang W., and Li M^. (2018) Sorting of a Multi-subunit Ubiquitin Ligase Complex in the Endolysosome System, eLife pii: e33116.
- Zhu L*., Jorgensen JR*., Li M., Chuang YS., Emr SD.(2017) ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins, eLife pii: e26403
Before U of M
- Li M., Koshi T. and Emr SD. (2015) Membrane-anchored ubiquitin ligase complex required for the turn-over of lysosomal membrane proteins, J. Cell Biol. 211(3)639-52
- Li M., Rong Y., Chuang Y., Peng D. and Emr SD. (2015) Ubiquitin-dependent lysosomal membrane protein sorting and degradation, Mol. Cell 57(3):467-78
- Inoue H., Li M. and Schnell DJ. (2013) An essential role for chloroplast heat shock protein 90 (Hsp90C) in protein import into chloroplasts, PNAS 110(8):3173-8
- Van Gisbergen P*., Li M*., Wu S. and Bezanilla M. (2012) PI(3,5)P2 is critical for formin-mediated polarized growth, J. Cell Biol. 198(2):235-50, *:Equal contribution. Featured by an editorial. Recommended by F1000
- Viana A., Li M., and Schnell DJ. (2010) Determinants for stop-transfer and post-import pathways for protein targeting to the chloroplast inner envelope membrane, J. Biol. Chem. 285(17):12948-60
- Vidali L., Gisbergen P., Guérin C., Franco P., Li M., Burkart G., Augustine R., Blanchoin L., and Bezanilla M. (2009) Rapid formin-mediated actin-filament elongation is essential for polarized plant cell growth, PNAS 106(32):13341-6.
- Singh DN*., Li M*., Lee SB., Schnell DJ. and Daniell H. (2008) Tic40 expression in chloroplast results in massive proliferation of the inner envelope membrane, Plant Cell 20(12):3405-17 *:Equal contribution. The cover story.
- Li M. and Schnell DJ.(2006) Reconstitution of protein targeting to the inner envelope membrane of chloroplasts, J. Cell Biol. 175(2):249-59. Featured by an editorial. Recommended by F1000.
- Inaba T, Alvarez-Huerta M, Li M, Bauer J, Ewers C, Kessler F, Schnell DJ.(2005) Arabidopsis Tic110 is essential for the assembly and function of the protein import machinery of plastids, Plant Cell. 17(5):1482-96
- Inaba T., Li M., Alvarez-Huerta M., Kessler F., and Schnell DJ. (2003) atTic110 Functions as a Scaffold for Coordinating the Stromal Events of Protein Import into Chloroplasts, J. Biol. Chem. 278. 38617-386271