The current Ruotolo group enjoying a reunion with alumni at ASMS 2018. (Front to back) Left row: James, Suggie, Brandon, Linjie, Molly, Daniel, Varun; Right row: Chunyi, Yuwei, Jess, Sarah, Carolina, Dan, Michael.
The Ruotolo Group at the ASMS 2018 closing ceremony on the USS Midway. (left to right) back row : Varun, Sarah, Suggie, Dan; Front Row: Chunyi, Daniel, Yuwei, Carolina
Below are the exciting research topics presented at ASMS from our group.
Yuwei Tian – ThOD: Novel Hydrogen/Deuterium Exchange Mass Spectrometry Method for Biopharmaceutical Characterization at High Concentrations
Daniel A. Polasky – TOB: CIUSuite 2: Next-Generation Software for the Analysis of Gas-Phase Protein Unfolding Data
Sugyan Dixit – ThOH: Ion Mobility-Mass Spectrometry and Hybrid Computational Modeling Reveal Detailed Models of Amyloid Peptide Membrane Interactions
Varun V. Gadkari – TP 428: Ion Mobility-Mass Spectrometry Based Characterization of MOAG-4: An Intrinsically Disordered Protein Implicated in Neurodegenerative Disease
Sarah M. Fantin – WP 434: Classifying Ligand Binding Behavior of the Integral Membrane Translocator Protein (TSPO) via Collision Induced Unfolding from Micelles and Nanodiscs
Chunyi Zhao – TP 425: Gas-Phase Unfolding Reveals Stability Shifts in Substrate-Bound Modular Polyketide Synthases
Daniel D. Vallejo – TP 417: Rapid, Parallelized Collision Induced Unfolding of Intact Antibodies: The Influence of Excipients on Antibody Charge Stripping
Carolina Rojas Ramirez – TP 549: Negative-Ion Mode Mass Spectrometry for Revealing Interaction Sites within RNA-Protein Complexes by Selective Infrared Multiphoton Dissociation of RNAPeptide Crosslinked Species
Michael Keating – TP 757 Altering the Charge-Pairing Environment within Tagged Protein Complexes for Improved Top-Down Sequencing