Our lab is equipped with an ion mobility-mass spectrometry instrument in the form of the 6560 IM-Q-ToF instrument (Agilent). This is a new primary instrument used in our labs research.
The Agilent 6560 differs from the Synapt instrumentation. The 6560 has a different instrument schematic where the quadrupole and collision cell are subsequent to IMS seperation. The IMS cell is a 1-meter drift tube, and operates as a uniform field compared to the Synapt travelling wave. Lastly, the 6560 in our lab contains modifications to the source region and the addition of sulfur hexafluoride gas. These modification enable more activating conditions to unfolding large protein complexes. (Please refer to Stow S.M., et al., Analytical Chemistry, 2017, 89 (17) and Kurulugama R.T., et al., Analyst, 2015, 140 (20) for more details.)
- Welcome Addison, Hanyu, and Ryan!
- Congratulations to Iliana!
- Congratulations to Dr. Rojas Ramirez and Dr. Parson!
- Congratulations to Dr. Han!
- New Publication from the Ruotolo Lab Featured in UM News!
Contact
Ruotolo Group
University of Michigan
Department of Chemistry
Room 4550
930 N. University Ave, Ann Arbor, MI 48109-1055
Phone: (+1) 734-763-2443
Fax: (1+) 734-615-3718